Wound healing is one of the most complex processes in the human body. It involves the
spatial and temporal synchronization of a variety of cell types with distinct roles in the …

Wound healing (WH) and the role fibroblasts play in the process, as well as healing
impairment and fibroblast dysfunction, have been thoroughly reviewed by other authors. We …

Diabetic ulcer is the most common kind of chronic wound worldwide. Though great efforts
have been devoted, diabetic ulcer still remains as a challenge that requires constant …

Background: Delayed wound healing in diabetic patients is one of the most challenging
complications in clinical medicine, as it poses a greater risk of gangrene, amputation and …

Although chronic wounds are common and continue to be a major cause of morbidity and
mortality, treatments for these conditions are lacking and often ineffective. A large body of …

The development of molecular biology and other new biotechnologies helps us to recognize
the wound healing and non-healing wound of skin in the past 30 years. This review mainly …

The vascular network delivers oxygen (O2) and nutrients to all cells within the body. It is
therefore not surprising that O2 availability serves as a primary regulator of this complex …

This is the first installment of 2 articles that discuss the biology and pathophysiology of
wound healing, review the role that growth factors play in this process, and describe current …

Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …

Angiogenesis plays a crucial role in wound healing by forming new blood vessels from
preexisting vessels by invading the wound clot and organizing into a microvascular network …