Sensing and signaling of methionine metabolism

L Lauinger, P Kaiser - Metabolites, 2021 - mdpi.com
Availability of the amino acid methionine shows remarkable effects on the physiology of
individual cells and whole organisms. For example, most cancer cells, but not normal cells …

Regulation of translation by one-carbon metabolism in bacteria and eukaryotic organelles

S Shetty, U Varshney - Journal of Biological Chemistry, 2021 - ASBMB
Protein synthesis is an energetically costly cellular activity. It is therefore important that the
process of mRNA translation remains in excellent synchrony with cellular metabolism and its …

The Swi-Snf chromatin remodeling complex mediates gene repression through metabolic control

MC Church, A Price, H Li… - Nucleic Acids Research, 2023 - academic.oup.com
In eukaryotes, ATP-dependent chromatin remodelers regulate gene expression in response
to nutritional and metabolic stimuli. However, altered transcription of metabolic genes may …

Surviving in the Brine: A Multi-Omics Approach for Understanding the Physiology of the Halophile Fungus Aspergillus sydowii at Saturated NaCl Concentration

I Jiménez-Gómez, G Valdés-Muñoz… - Frontiers in …, 2022 - frontiersin.org
Although various studies have investigated osmoadaptations of halophilic fungi to saline
conditions, only few analyzed the fungal mechanisms occurring at saturated NaCl …

Transcriptional Profiles of a Foliar Fungal Endophyte (Pestalotiopsis, Ascomycota) and Its Bacterial Symbiont (Luteibacter, Gammaproteobacteria) Reveal Sulfur …

JP Shaffer, ME Carter, JE Spraker, M Clark, BA Smith… - Msystems, 2022 - Am Soc Microbiol
Symbiosis with bacteria is widespread among eukaryotes, including fungi. Bacteria that live
within fungal mycelia (endohyphal bacteria) occur in many plant-associated fungi, including …

The SWI/SNF chromatin remodeling complex: a critical regulator of metabolism

MC Church, JL Workman - Biochemical Society Transactions, 2024 - portlandpress.com
The close relationship between chromatin and metabolism has been well-studied in recent
years. Many metabolites have been found to be cofactors used to modify chromatin, and …

Enhanced ribonucleic acid production by high-throughput screening based on fluorescence activation and transcriptomic-guided fermentation optimization in …

Y Wu, S Lei, C Lu, J Li, G Du, Y Liu - Journal of Agricultural and …, 2023 - ACS Publications
Currently, the primary source of ribonucleic acids (RNAs), which is used as a flavor
enhancer and nutritional supplement in the food manufacturing and processing industries …

The role of methionine synthases in fungal metabolism and virulence

J Scott, J Amich - Essays in Biochemistry, 2023 - portlandpress.com
Methionine synthases (MetH) catalyse the methylation of homocysteine (Hcy) with 5-methyl-
tetrahydrofolate (5, methyl-THF) acting as methyl donor, to form methionine (Met) and …

Methionine uptake via the SLC43A2 transporter is essential for regulatory T-cell survival

N Saini, A Naaz, SP Metur, P Gahlot… - Life Science …, 2022 - life-science-alliance.org
Cell death, survival, or growth decisions in T-cell subsets depend on interplay between
cytokine-dependent and metabolic processes. The metabolic requirements of T-regulatory …

ATP sulfurylase atypical leucine zipper interacts with Cys3 and calcineurin A in the regulation of sulfur amino acid biosynthesis in Cryptococcus neoformans

JP da Silva, MR Meneghini, RS Santos, VL Alves… - Scientific Reports, 2023 - nature.com
Fungal pathogens are a major cause of death, especially among immunocompromised
patients. Therapies against invasive fungal infections are restricted to a few antifungals; …