Cyclosporine, the prototype calcineurin inhibitor, transformed immunosuppressant regimens
and practices post-organ transplantation. Therapeutic uses of cyclosporine branched out to …

Arterial hypertension is a considerable side effect that accompanies the clinical use of
immunosuppressant drugs such as cyclosporine (CSA). In addition to promoting graft …

Diabetic nephropathy is a major health challenge with considerable economic burden and
significant impact on patients' quality of life. Despite recent advances in diabetic patient care …

Chrysin and luteolin are two important plant flavonoids. In the present study, we
hypothesized that they protect against deleterious vascular effects of diabetes. Diabetes was …

The onset of vascular impairment precedes that of diagnostic hyperglycemia in diabetic
patients suggesting a vascular insult early in the course of metabolic dysfunction without a …

Nephrotoxicity is a major side effect for the antineoplastic drug cisplatin. Here, we employed
pharmacological, biochemical, and molecular studies to investigate the role of peroxisome …

Electrospun nanofibers (NFs) as drug delivery/tissue regeneration template and
antimicrobial photodynamic therapy (APDT) have been widely investigated as two different …

The cardiovascular and renovascular complications of metabolic deterioration are
associated with localized adipose tissue dysfunction. We have previously demonstrated that …

Oxidative stress causes hypoadiponectemia and reactive oxygen species production. This
study investigates the pathophysiological role and potential effects of adiponectin with …

Oxidative stress, which is associated with metabolic and anthropometric perturbations, leads
to reactive oxygen species production and decrease in plasma adiponectin concentration …