[HTML][HTML] The interplay of immunology and cachexia in infection and cancer
H Baazim, L Antonio-Herrera… - Nature Reviews …, 2022 - nature.com
Diverse inflammatory diseases, infections and malignancies are associated with wasting
syndromes. In many of these conditions, the standards for diagnosis and treatment are …
syndromes. In many of these conditions, the standards for diagnosis and treatment are …
[HTML][HTML] Cancer cachexia: molecular mechanisms and treatment strategies
T Setiawan, IN Sari, YT Wijaya, NM Julianto… - Journal of Hematology & …, 2023 - Springer
Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …
Cancer cachexia: more than skeletal muscle wasting
SF Schmidt, M Rohm, S Herzig, MB Diaz - Trends in cancer, 2018 - cell.com
Cancer cachexia is a multifactorial condition characterized by body weight loss that
negatively affects quality of life and survival of patients with cancer. Despite the clinical …
negatively affects quality of life and survival of patients with cancer. Despite the clinical …
[HTML][HTML] Contribution of adipose tissue to development of cancer
AJ Cozzo, AM Fuller, L Makowski - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
Solid tumor growth and metastasis require the interaction of tumor cells with the surrounding
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …
tissue, leading to a view of tumors as tissue-level phenomena rather than exclusively cell …
[HTML][HTML] The role of tumor microenvironment cells in colorectal cancer (CRC) cachexia
A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Cancer cachexia (CC) is a multifactorial syndrome in patients with advanced cancer
characterized by weight loss via skeletal-muscle and adipose-tissue atrophy, catabolic …
characterized by weight loss via skeletal-muscle and adipose-tissue atrophy, catabolic …
[HTML][HTML] Altered regulation of mesenchymal cell senescence in adipose tissue promotes pathological changes associated with diabetic wound healing
A Kita, Y Saito, N Miura, M Miyajima… - Communications …, 2022 - nature.com
Pathologic diabetic wound healing is caused by sequential and progressive deterioration of
hemostasis, inflammation, proliferation, and resolution/remodeling. Cellular senescence …
hemostasis, inflammation, proliferation, and resolution/remodeling. Cellular senescence …
[HTML][HTML] Transforming growth factor beta superfamily regulation of adipose tissue biology in obesity
MJ Lee - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Accumulation of dysfunctional white adipose tissues increases risks for cardiometabolic
diseases in obesity. In addition to white, brown or brite adipose tissues are also present in …
diseases in obesity. In addition to white, brown or brite adipose tissues are also present in …
[HTML][HTML] Human cachexia induces changes in mitochondria, autophagy and apoptosis in the skeletal muscle
GS de Castro, E Simoes, JDCC Lima, M Ortiz-Silva… - Cancers, 2019 - mdpi.com
Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle
mass due to imbalance between protein synthesis and degradation, which is related with …
mass due to imbalance between protein synthesis and degradation, which is related with …
[HTML][HTML] Elevated serum interleukin-8 level correlates with cancer-related cachexia and sarcopenia: an indicator for pancreatic cancer outcomes
YC Hou, CJ Wang, YJ Chao, HY Chen… - Journal of clinical …, 2018 - mdpi.com
Cancer cachexia (CC), characterized by body weight loss and sarcopenia, contributes to
over 20% of all cancer-related death. Approximately 80% of pancreatic cancer (PC) patients …
over 20% of all cancer-related death. Approximately 80% of pancreatic cancer (PC) patients …
[HTML][HTML] Transforming growth factor-beta signaling in cancer-induced cachexia: from molecular pathways to the clinics
R Balsano, Z Kruize, M Lunardi, A Comandatore… - Cells, 2022 - mdpi.com
Cachexia is a metabolic syndrome consisting of massive loss of muscle mass and function
that has a severe impact on the quality of life and survival of cancer patients. Up to 20% of …
that has a severe impact on the quality of life and survival of cancer patients. Up to 20% of …