[HTML][HTML] Ultrasound-responsive cavitation nuclei for therapy and drug delivery

K Kooiman, S Roovers, SAG Langeveld… - Ultrasound in medicine …, 2020 - Elsevier
Therapeutic ultrasound strategies that harness the mechanical activity of cavitation nuclei for
beneficial tissue bio-effects are actively under development. The mechanical oscillations of …

Applications of acoustics and cavitation to noninvasive therapy and drug delivery

CC Coussios, RA Roy - Annu. Rev. Fluid Mech., 2008 - annualreviews.org
Biomedical acoustics is rapidly evolving from a diagnostic modality into a therapeutic tool,
and acoustic cavitation is often the common denominator in a wide range of new therapeutic …

Ultrasound‐propelled nanocups for drug delivery

JJ Kwan, R Myers, CM Coviello, SM Graham, AR Shah… - small, 2015 - Wiley Online Library
Ultrasound‐induced bubble activity (cavitation) has been recently shown to actively
transport and improve the distribution of therapeutic agents in tumors. However, existing …

Doxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery …

P Mohan, N Rapoport - Molecular pharmaceutics, 2010 - ACS Publications
Doxorubicin (DOX) is one of the most commonly used chemotherapeutic drugs and is a
popular research tool due to the inherent fluorescence of the DOX molecule. After DOX …

Role of acoustic cavitation in the delivery and monitoring of cancer treatment by high-intensity focused ultrasound (HIFU)

CC Coussios, CH Farny, G Ter Haar… - International journal of …, 2007 - Taylor & Francis
Acoustic cavitation has been shown to play a key role in a wide array of novel therapeutic
ultrasound applications. This paper presents a brief discussion of the physics of thermally …

High-intensity focused ultrasound: past, present, and future in neurosurgery

SA Quadri, M Waqas, I Khan, MA Khan, SS Suriya… - Neurosurgical …, 2018 - thejns.org
Since Lynn and colleagues first described the use of focused ultrasound (FUS) waves for
intracranial ablation in 1942, many strides have been made toward the treatment of several …

Phase‐shift, stimuli‐responsive perfluorocarbon nanodroplets for drug delivery to cancer

N Rapoport - Wiley Interdisciplinary Reviews: Nanomedicine …, 2012 - Wiley Online Library
This review focuses on phase‐shift perfluorocarbon nanoemulsions whose action depends
on an ultrasound‐triggered phase shift from a liquid to gas state. For drug‐loaded …

Liposomes in ultrasonic drug and gene delivery

SL Huang - Advanced drug delivery reviews, 2008 - Elsevier
Liposome-based drug and gene delivery systems have potential for significant roles in a
variety of therapeutic applications. Recently, liposomes have been used to entrap gas and …

Nucleation, mapping and control of cavitation for drug delivery

E Stride, C Coussios - Nature Reviews Physics, 2019 - nature.com
Acoustically driven bubbles produce a range of mechanical, thermal and chemical effects
that can be exploited in drug delivery applications. Significant improvements in the targeting …

Image-guided ultrasound phased arrays are a disruptive technology for non-invasive therapy

K Hynynen, RM Jones - Physics in Medicine & Biology, 2016 - iopscience.iop.org
Focused ultrasound offers a non-invasive way of depositing acoustic energy deep into the
body, which can be harnessed for a broad spectrum of therapeutic purposes, including …