Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …

Simple Summary Chemotherapy is a key modality in today's practice of clinical oncology.
The potential for systemic treatment of cancer patients with cytotoxic agents was discovered …

Background Intrinsic or acquired resistance to epidermal growth factor receptor-tyrosine
kinase inhibitors (EGFR-TKIs) is common, thus strategies for the management of EGFR-TKIs …

Malignant pleural mesothelioma (MPM) is a lethal thoracic malignancy whose incidence is
still increasing worldwide. MPM is characterized by frequent inactivation of tumor …

Background Histone acetylation/deacetylase process is one of the most studied epigenetic
modifications. Histone deacetylase inhibitors (HDACis) have shown clinical benefits in …

Simple Summary Ferroptosis is increasingly recognized as a promising avenue for cancer
therapy, while the biomarkers that predict the sensitivity and/or resistance of ferroptosis and …

Malignant pleural mesothelioma (MPM) is a lethal malignancy etiologically caused by
asbestos exposure, for which there are few effective treatment options. Although asbestos …

Malignant pleural mesothelioma (MPM) is a rare, aggressive cancer of the mesothelial cells
lining the pleural surface of the chest wall and lung. The etiology of MPM is strongly …

Background Metastasis remains one of the greatest challenges involved in treating gastric
cancer (GC). Ropivacaine (Rop) is not only a well-documented local anesthetic medicament …

Simple Summary Malignant pleural mesothelioma (MPM) is an extremely lethal cancer,
notoriously known for its limited treatment options, lack of targeted therapies, and …