The gastroprotective effect of menthol: involvement of anti-apoptotic, antioxidant and anti-inflammatory activities

AL Rozza, F Meira de Faria, AR Souza Brito… - PloS one, 2014 - journals.plos.org
The aim of this research was to investigate the anti-apoptotic, antioxidant and anti-
inflammatory properties of menthol against ethanol-induced gastric ulcers in rats. Wistar rats …

Amelioration of ethanol-induced gastric ulcer in rats by quercetin: implication of Nrf2/HO1 and HMGB1/TLR4/NF-κB pathways

SGE Shams, RG Eissa - Heliyon, 2022 - cell.com
Gastric ulcer is a serious medical condition that can be developed due to an imbalance in
the protective and destructive factors of the gastric system. Available therapies do not …

[HTML][HTML] Chemical and biological aspects of extracts from medicinal plants with antidiabetic effects

LF Gushiken, FP Beserra, AL Rozza… - The review of diabetic …, 2016 - ncbi.nlm.nih.gov
Diabetes mellitus is a chronic disease and a leading cause of death in western countries.
Despite advancements in the clinical management of the disease, it is not possible to control …

Formulation, optimization and characterization of allantoin-loaded chitosan nanoparticles to alleviate ethanol-induced gastric ulcer: in-vitro and in-vivo studies

RM Aman, RA Zaghloul, MS El-Dahhan - Scientific reports, 2021 - nature.com
Allantoin (ALL) is a phytochemical possessing an impressive array of biological activities.
Nonetheless, developing a nanostructured delivery system targeted to augment the gastric …

Huang-Qi-Jian-Zhong-Tang accelerates healing of indomethacin-induced gastric ulceration in rats via anti-inflammatory and antioxidant mechanisms

H Song, M Xiong, C Yu, B Ren, M Zhong, S Zhou… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Huang-Qi-Jian-Zhong-Tang (HQJZT) is a
canonical traditional Chinese medicine (TCM) formula that has been widely used in both the …

The effect of metformin on indomethacin-induced gastric ulcer: Involvement of nitric oxide/Rho kinase pathway

EY AbdelAziz, MG Tadros, ET Menze - European Journal of Pharmacology, 2021 - Elsevier
Gastric ulcer is a very common disease that represent an economic burden. Non-steroidal
anti-inflammatory drugs induce ulcer in old patients and in patients with comorbidities …

Vitamin E: A potential therapy for gastric mucosal injury

Y Kamisah, HMS Qodriyah, KH Chua… - Pharmaceutical …, 2014 - Taylor & Francis
Context: Many scientific reports have shown the involvement of oxidative stress and
inflammation as well as diminished gastroprotective substances in the pathogenesis of …

C‐phycocyanin protects against ethanol‐induced gastric ulcers in rats: Role of HMGB1/NLRP3/NF‐κB pathway

AA Alzokaky, EM Abdelkader… - Basic & Clinical …, 2020 - Wiley Online Library
Gastric ulcer is a widespread inflammatory disease with high socio‐economic burden. C‐
phycocyanin is one of the active constituents of Spirulina microalgae, and although it is well …

Protective effect of butyrate against ethanol-induced gastric ulcers in mice by promoting the anti-inflammatory, anti-oxidant and mucosal defense mechanisms

J Liu, F Wang, H Luo, A Liu, K Li, C Li… - International …, 2016 - Elsevier
Gastric ulcers (GUs) are a common type of peptic ulcer. Alcohol overdose is one of the main
causes of GU, which is difficult to prevent. Although the protective effect of butyrate on …

Diabetes is an independent risk factor for peptic ulcer bleeding: A nationwide population‐based cohort study

YL Peng, HB Leu, JC Luo, CC Huang… - Journal of …, 2013 - Wiley Online Library
Abstract Background and Aims Diabetic patients reportedly have a higher incidence of
peptic ulcer disease. The aim of this study was to investigate if type II diabetic patients have …