Osteoarthritis (OA) is one of the most common causes of disability around the globe,
especially in aging populations. The main symptoms of OA are pain and loss of motion and …

Osteoarthritis (OA) represents an enduring and widespread global burden, causing
significant morbidity and disability, whose pathology is characterized by persistent …

The Human Mesenchymal Stem Cell (hMSC) secretome has pleiotropic effects
underpinning its therapeutic potential. hMSC serum-free conditioned media (SFCM) …

The human mesenchymal stem cell (hMSC) secretome has pleiotropic effects which
underpin their therapeutic potential. hMSC serum-free conditioned media (SFCM) has been …

Hyaline cartilage is deficient in self-healing properties. The early treatment of focal cartilage
lesions is a public health challenge to prevent long-term degradation and the occurrence of …

Articular cartilage covers the surface of synovial joints and enables joint movement.
However, it is susceptible to progressive degeneration with age that can be accelerated by …

The term “osteoimmunology” was coined to denote the bridge between the immune system
and the skeletal system. Osteoimmunology is interdisciplinary, and a full understanding and …

Background Osteoarthritis (OA) progression involves multiple factors, including cartilage
erosion as the basic pathological mechanism of degeneration, and is closely related to …

Human adult mesenchymal stromal cells (MSCs) from a variety of sources may be used to
repair defects in articular cartilage by inducing them into chondrogenic differentiation. The …

In biology, collagen-biomaterial regulates several signaling mechanisms of bone and
immune cells involved in tissue repair and any imbalance in collagen turnover may affect the …