Lipids entering the gastrointestinal tract include dietary lipids (triacylglycerols, cholesteryl
esters and phospholipids) and endogenous lipids from bile (phospholipids and cholesterol) …

Triglyceride molecules represent the major form of storage and transport of fatty acids within
cells and in the plasma. The liver is the central organ for fatty acid metabolism. Fatty acids …

Lipid synthesis is necessary for formation of epithelial barriers and homeostasis with
external microbes. An analysis of the response of human keratinocytes to several different …

The gut microbiota play important roles in lipid metabolism and absorption. However, the
contribution of the small bowel microbiota of mammals to these diet-microbe interactions …

Lipid droplets (LDs) are ubiquitous organelles that store neutral lipids for energy or
membrane synthesis and act as hubs for metabolic processes. Cells generate LDs de novo …

Non-alcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease
worldwide. It is characterised by steatosis, liver inflammation, hepatocellular injury and …

Fatty acids are the most efficient substrates for energy production in vertebrates and are
essential components of the lipids that form biological membranes. Synthesis of …

Whereas the cellular and molecular features of human inflammatory skin diseases are well
characterized, their tissue context and systemic impact remain poorly understood. We thus …

The prevalence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, yet there
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …

Triglyceride (TG) storage in adipose tissue provides the major reservoir for metabolic energy
in mammals. During lipolysis, fatty acids (FAs) are hydrolyzed from adipocyte TG stores and …