The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …

As the major cellular component of the innate immune system in the central nervous system
(CNS) and the first line of defense whenever injury or disease occurs, microglia play a …

Chronic neuroinflammation with sustained microglial activation occurs following severe
traumatic brain injury (TBI) and is believed to contribute to subsequent neurodegeneration …

A single traumatic brain injury is associated with an increased risk of dementia and, in a
proportion of patients surviving a year or more from injury, the development of hallmark …

Traumatic brain injury (TBI) remains one of the leading causes of mortality and morbidity
worldwide, yet despite extensive efforts to develop neuroprotective therapies for this …

Recent clinical studies indicate that traumatic brain injury (TBI) produces chronic and
progressive neurodegenerative changes leading to late neurologic dysfunction, but little is …

Activated microglia and macrophages exert dual beneficial and detrimental roles after
central nervous system injury, which are thought to be due to their polarization along a …

Determining regions of altered brain physiology after diffuse brain injury is challenging.
Microglia, brain immune cells with ramified and dynamically moving processes, constantly …

Traumatic brain injury (TBI) has been linked to dementia and chronic neurodegeneration.
Described initially in boxers and currently recognized across high contact sports, the …

It has long been suggested that prior traumatic brain injury (TBI) increases the subsequent
incidence of chronic neurodegenerative disorders, including Alzheimer disease, Parkinson …