Tetrazole derivatives as promising anticancer agents

EA Popova, AV Protas… - Anti-Cancer Agents in …, 2017 - ingentaconnect.com
Tetrazole cycle is a promising pharmacophore fragment frequently used in the development
of novel drugs. This moiety is a stable, practically non-metabolized bioisosteric analog of …

Fluorescence “Turn On–Off” sensing of copper (II) ions utilizing coumarin–based chemosensor: experimental study, theoretical calculation, mineral and drinking water …

FN Arslan, GA Geyik, K Koran, F Ozen, D Aydin… - Journal of …, 2020 - Springer
Herein, we report the preparation of a fluorescent sensor based on coumarin derivative for
copper (II) ion sensing in CH 3 CN/HEPES media. 6, 7–dihydroxy–3–(4–(trifluoro) …

Coumarin Based Highly Selective “off-on-off” Type Novel Fluorescent Sensor for Cu2+ and S2− in Aqueous Solution

ŞN Karuk Elmas, F Ozen, K Koran, I Yilmaz… - Journal of …, 2017 - Springer
Abstract Solvent free synthesis of 6, 7-dihydroxy-3-(3-chlorophenyl) coumarin (CFHC) was
designed and obtained by the interaction of 2-(2, 4, 5-trimethoxyphenyl)-1-(3-chlorophenyl) …

Synthesis, structural and thermal characterizations and in vitro cytotoxic activities of new cyclotriphosphazene derivatives

K Koran, Ç Tekin, E Çalışkan, S Tekin… - … , Sulfur, and Silicon …, 2017 - Taylor & Francis
We investigated the cytotoxic effects of the newly synthesized cyclotriphosphazene
derivatives on A2780 (ovarian), PC-3 and LNCaP (prostate) cancer cell lines. 4′-hydroxy …

Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents

JR Baker, CC Russell, J Gilbert, A McCluskey… - RSC medicinal …, 2021 - pubs.rsc.org
We have identified specific dichlorophenylacrylonitriles as lead compounds in the
development of novel anticancer compounds, notably,(Z)-N-(4-(2-cyano-2-(3, 4 …

Phosphorus–nitrogen compounds. Part 37. Syntheses and structural characterizations, biological activities of mono and bis (4-fluorobenzyl) …

G Elmas, A Okumuş, P Sevinç, Z Kılıç, L Açık… - New Journal of …, 2017 - pubs.rsc.org
The Cl substitution reactions of octachlorocyclotetraphosphazene, N4P4Cl8, with one
equimolar amount of (4-fluorobenzyl) diamines (1–3) affords mono (4-fluorobenzyl) …

Quantitative analysis of weak non-covalent interactions in (Z)-3-(4-halophenyl)-2-(pyridin-2/3/4-yl) acrylonitriles

P Venkatesan, M Cerón, S Thamotharan, F Robles… - …, 2018 - pubs.rsc.org
A detailed experimental and theoretical investigation on the intermolecular interactions in (Z)-
3-(4-halophenyl)-2-(pyridin-2/3/4-yl) acrylonitriles is reported. The intermolecular …

An ultrasensitive and selective 'turn off'fluorescent sensor with simple operation for the determination of trace copper (II) ions in water and various beverage samples

SN Karuk Elmas, IB Gunay, K Koran… - Supramolecular …, 2019 - Taylor & Francis
Considering vital roles of trace copper ions for the health of humans, it is critical to
sensitively detect it in foodstuffs. Herein, an ultrasensitive and cost–effective coumarin based …

Synthesis, structural and thermal characterizations, dielectric properties and in vitro cytotoxic activities of new 2, 2, 4, 4-tetra (4′-oxy-substituted-chalcone)-6, 6 …

K Koran, Ç Tekin, F Biryan, S Tekin, S Sandal… - Medicinal Chemistry …, 2017 - Springer
In this study, we aimed to investigate the relationship between the cytotoxic and dielectric
properties of newly synthesized 2, 2, 4, 4-tetra (4′-oxy-substituted-chalcone)-6, 6 …

Phytochemical Compounds and Biological Activities of Celtis tournefortii Fruits

S Keser, F Keser, O Kaygili, S Tekin… - Analytical Chemistry …, 2017 - Taylor & Francis
It is known that Celtis species have been used in healing wound, epilepsy crisis, and
stomach pain among the people. The antiradical (DPPH, OH, ABTS) activities …