New psychoactive stimulants and psychedelics continue to play an important role on the
illicit new psychoactive substance (NPS) market. Designer stimulants and psychedelics both …

Aminorex (5-phenyl-4, 5-dihydro-1, 3-oxazol-2-amine) and 4-methylaminorex (4-methyl-5-
phenyl-4, 5-dihydro-1, 3-oxazol-2-amine) are psychostimulants that have long been listed in …

α-Pyrrolidinohexiophenone (α-PHP) is the one-carbon unit α-extended homolog of the better-
known and widely abused synthetic cathinone central stimulant α-PVP (“flakka”); both are …

A new generation of novel cathinone compounds has been developed as stimulant
substitutes to avoid drug control laws and detection of use by blood tests. Dipentylone, N …

Synthetic cathinones are a class of new psychoactive substances that induce
psychostimulant effects and pose risk for hospitalizations, overdose, and death. At the …

The illicit drug market of novel psychoactive substances (NPSs) is expanding, becoming an
alarming threat due to increasing intoxication cases and insufficient (if any) knowledge of …

Clandestine chemists are currently exploiting the pyrrolidinophenone scaffold to develop
new designer drugs that carry the risk of abuse and overdose. These drugs promote …

Methiopropamine is a novel psychoactive substance (NPS) that is associated with several
cases of clinical toxicity, yet little information is available regarding its neuropharmacological …

Substitutions to the phenethylamine structure give rise to numerous amphetamines and
cathinones, contributing to an ever-growing number of abused novel psychoactive …

Abstract (±)-cis-4, 4′-Dimethylaminorex (4, 4′-DMAR) is a new psychoactive substance
(NPS) that has been associated with 31 fatalities and other adverse events in Europe …