Exposure to per-and polyfluoroalkyl substances and markers of liver injury: a systematic review and meta-analysis

E Costello, S Rock, N Stratakis, SP Eckel… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Experimental evidence indicates that exposure to certain pollutants is
associated with liver damage. Per-and polyfluoroalkyl substances (PFAS) are persistent …

Per‐and polyfluoroalkyl substance toxicity and human health review: Current state of knowledge and strategies for informing future research

SE Fenton, A Ducatman, A Boobis… - Environmental …, 2021 - Wiley Online Library
Reports of environmental and human health impacts of per‐and polyfluoroalkyl substances
(PFAS) have greatly increased in the peer‐reviewed literature. The goals of the present …

PFAS molecules: a major concern for the human health and the environment

E Panieri, K Baralic, D Djukic-Cosic, A Buha Djordjevic… - Toxics, 2022 - mdpi.com
Per-and polyfluoroalkyl substances (PFAS) are a group of over 4700 heterogeneous
compounds with amphipathic properties and exceptional stability to chemical and thermal …

[HTML][HTML] Exposure to a mixture of legacy, alternative, and replacement per-and polyfluoroalkyl substances (PFAS) results in sex-dependent modulation of cholesterol …

K Roth, Z Yang, M Agarwal, W Liu, Z Peng… - Environment …, 2021 - Elsevier
Background Epidemiological studies have shown Per-and polyfluoroalkyl substances
(PFAS) to be associated with diseases of dysregulated lipid and sterol homeostasis such as …

Risk to human health related to the presence of perfluoroalkyl substances in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Risk to human health related to the presence of perfluorooctane sulfonic acid and perfluorooctanoic acid in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2018 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluorooctane sulfonic acid (PFOS) and …

Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?

S Fragki, H Dirven, T Fletcher… - Critical reviews in …, 2021 - Taylor & Francis
Associations between per-and polyfluoroalkyl substances (PFASs) and increased blood
lipids have been repeatedly observed in humans, but a causal relation has been debated …

β-Cyclodextrin polymer network sequesters perfluorooctanoic acid at environmentally relevant concentrations

L Xiao, Y Ling, A Alsbaiee, C Li… - Journal of the …, 2017 - ACS Publications
Per-and poly fluorinated alkyl substances (PFASs), notably perfluorooctanoic acid (PFOA),
contaminate many ground and surface waters and are environmentally persistent. The …

Assessing the human health risks of per-and polyfluoroalkyl substances: a need for greater focus on their interactions as mixtures

AF Ojo, C Peng, JC Ng - Journal of Hazardous Materials, 2021 - Elsevier
Humans are exposed to complex mixtures of per-and polyfluoroalkyl substances (PFAS).
However, human health risk assessment of PFAS currently relies on animal toxicity data …