The therapeutic potential of apigenin

B Salehi, A Venditti, M Sharifi-Rad, D Kręgiel… - International journal of …, 2019 - mdpi.com
Several plant bioactive compounds have exhibited functional activities that suggest they
could play a remarkable role in preventing a wide range of chronic diseases. The largest …

A review on flavonoid apigenin: Dietary intake, ADME, antimicrobial effects, and interactions with human gut microbiota

M Wang, J Firrman, LS Liu… - BioMed research …, 2019 - Wiley Online Library
Apigenin is a flavonoid of low toxicity and multiple beneficial bioactivities. Published reviews
all focused on the findings using eukaryotic cells, animal models, or epidemiological studies …

Antioxidant-rich natural fruit and vegetable products and human health

AIO Jideani, H Silungwe, T Takalani… - … Journal of Food …, 2021 - Taylor & Francis
Antioxidants are important ingredients that are present in fruits and vegetables (FAV). With
increased consumption of FAV in its raw and processed form, a predominantly plant-based …

Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development

CR Ferraz, TT Carvalho, MF Manchope, NA Artero… - Molecules, 2020 - mdpi.com
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …

Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials

I Jantan, W Ahmad, SNA Bukhari - Frontiers in plant science, 2015 - frontiersin.org
The phagocyte–microbe interactions in the immune system is a defense mechanism but
when excessively or inappropriately deployed can harm host tissues and participate in the …

Health functionality of apigenin: A review

F Ali, Rahul, F Naz, S Jyoti… - International Journal of …, 2017 - Taylor & Francis
Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …

Flavones: from biosynthesis to health benefits

N Jiang, AI Doseff, E Grotewold - Plants, 2016 - mdpi.com
Flavones correspond to a flavonoid subgroup that is widely distributed in the plants, and
which can be synthesized by different pathways, depending on whether they contain C-or O …

Effects of flavonoids and other polyphenols on inflammation

R González, I Ballester, R López-Posadas… - Critical reviews in …, 2011 - Taylor & Francis
Flavonoids are a family of polyphenolic compounds which are widespread in nature
(vegetables) and are consumed as part of the human diet in significant amounts. There are …

Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages

X Zhang, G Wang, EC Gurley, H Zhou - PloS one, 2014 - journals.plos.org
Background Apigenin is a non-toxic natural flavonoid that is abundantly present in common
fruits and vegetables. It has been reported that apigenin has various beneficial health effects …

Photoprotection of natural flavonoids

N Saewan, A Jimtaisong - Journal of Applied Pharmaceutical …, 2013 - japsonline.com
Overexposure to ultraviolet (UV) radiation can cause a number of skin disorders such as
erythema, edema, hyperpigmentation, immunosuppression, photoaging, and skin cancer …