Systemic and radiation therapy approaches for locally advanced non–small-cell lung cancer

KA Higgins, S Puri, JE Gray - Journal of Clinical Oncology, 2022 - ascopubs.org
The treatment for locally advanced non–small-cell lung cancer has changed dramatically
over the past several years, with consolidative immunotherapy after concurrent …

[HTML][HTML] Non-Small Cell Lung Cancer Treatment with Molecularly Targeted Therapy and Concurrent Radiotherapy—A Review

K Król, A Mazur, P Stachyra-Strawa… - International Journal of …, 2023 - mdpi.com
Lung cancer is the leading cause of death worldwide for both men and women. Surgery can
be offered as a radical treatment at stages I and II and selected cases of stage III (III A) …

Erlotinib versus etoposide/cisplatin with radiation therapy in unresectable stage III epidermal growth factor receptor mutation-positive non-small cell lung cancer: a …

L Xing, G Wu, L Wang, J Li, J Wang, Z Yuan… - International Journal of …, 2021 - Elsevier
Purpose This study aimed to compare erlotinib (E) and etoposide/cisplatin (EP) with
concurrent radiation therapy (RT) for patients with stage IIIA/B unresectable advanced non …

Induction immune checkpoint inhibitors and chemotherapy before definitive chemoradiation therapy for patients with bulky unresectable stage III non-small cell lung …

Y Wang, T Zhang, J Wang, Z Zhou, W Liu, Z Xiao… - International Journal of …, 2023 - Elsevier
Purpose In the era of immunotherapy, the treatment for bulky, locally advanced non-small
cell lung cancer (LA-NSCLC) remains challenging. This study explored the feasibility of …

[HTML][HTML] Safety and tolerability of metastasis-directed radiation therapy in the era of evolving systemic, immune, and targeted therapies

E Guimond, CJ Tsai, A Hosni, G O'Kane, J Yang… - Advances in Radiation …, 2022 - Elsevier
AbstractPurpose: Systemic, immune, and target therapies are growing in use in the
management of metastatic cancers. The aim of this review was to describe up-to-date …

Targeted treatment for unresectable EGFR mutation-positive stage III non-small cell lung cancer: Emerging evidence and future perspectives

T Kato, I Casarini, M Cobo, C Faivre-Finn… - Lung Cancer, 2023 - Elsevier
Epidermal growth factor receptor (EGFR) mutations are detected in up to one third of
patients with unresectable stage III non-small cell lung cancer (NSCLC). The current …

[HTML][HTML] Combining radiotherapy with targeted therapies in non-small cell lung cancer: focus on anti-EGFR, anti-ALK and anti-angiogenic agents

A Wrona, R Dziadziuszko, J Jassem - Translational Lung Cancer …, 2021 - ncbi.nlm.nih.gov
The combination of radiotherapy (RT) with targeted agents in non-small cell lung cancer
(NSCLC) has been expected to improve the therapeutic ratio and tumor control. The EGFR …

Clinical outcomes and radiation pneumonitis after concurrent EGFR‐tyrosine kinase inhibitors and radiotherapy for unresectable stage III non‐small cell lung cancer

K Xu, J Liang, T Zhang, Z Zhou, D Chen… - Thoracic …, 2021 - Wiley Online Library
Background Concurrent epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐
TKI) with radiotherapy in patients with EGFR‐mutant unresectable stage III non‐small cell …

Safety and efficacy of combined radiotherapy, immunotherapy and targeted agents in elderly patients: a literature review

L Belgioia, I Desideri, A Errico, C Franzese… - Critical Reviews in …, 2019 - Elsevier
Purpose Aim of the present review is to assess present data about the use of the association
of Radiotherapy (RT) and targeted therapy/immunotherapy (TT/IT) in elderly people. Design …

Locally advanced, unresectable non-small cell lung cancer

S Puri, A Saltos, B Perez, X Le, JE Gray - Current oncology reports, 2020 - Springer
Abstract Purpose of Review Treatment of locally advanced, unresectable non-small cell lung
cancer (NSCLC) has recently been revolutionized by the incorporation of immunotherapy to …