Broad antibacterial spectrum, high oral bioavailability and excellent tissue penetration
combined with safety and few, yet rare, unwanted effects, have made the quinolones class of …

Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Quinolones are synthetic broad-spectrum antibiotics with good oral absorption and excellent
bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid …

Increasing development costs and higher failure rate in clinical trials has reduced the
repertoire of newer drugs in the market for clinical use. The most appropriate approach to …

Herein, three new mixed-ligand complexes were synthesized through the reaction of Fe (III),
Ni (II) and Cu (II) with moxifloxacin (MOX) in the presence of tri-substituted imidazole (TSI) to …

This review is aimed to provide extensive survey of quinolones and fluoroquinolones for a
variety of applications ranging from metal complexes and nanoparticle development to …

The water soluble mixed ligand copper (II) complexes of the type [Cu (sal)(diimine)(ClO4)]
21–5, where sal is salicylaldehyde and diimine is 2, 2′-bipyridine (bpy, 1), 1, 10 …

The water soluble mixed ligand complexes [Cu (nal)(diimine)(H 2 O)](ClO 4) 1–4, where H
(nal) is nalidixic acid and diimine is 2, 2′-bipyridine (1), 1, 10-phenanthroline (2), 5, 6 …

Cancer is a very risky life-threatening disease having most formidable afflictions in the world.
Several anticancer agents are commercially accessible, however, the emergence of …

In order to seek for new compounds with antitumor activity, our research group is focused on
copper complexes with mixed ligands. This work presents the synthesis and characterization …