ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum
F Reggiori, M Molinari - Physiological reviews, 2022 - journals.physiology.org
ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
(ER) within lysosomes or vacuoles. It is part of the self-digestion (ie, autophagic) programs …
ER-phagy at a glance
P Grumati, I Dikic, A Stolz - Journal of cell science, 2018 - journals.biologists.com
Selective autophagy represents the major quality control mechanism that ensures proper
turnover of exhausted or harmful organelles, among them the endoplasmic reticulum (ER) …
turnover of exhausted or harmful organelles, among them the endoplasmic reticulum (ER) …
ER‐phagy: shaping up and destressing the endoplasmic reticulum
S Wilkinson - The FEBS journal, 2019 - Wiley Online Library
The endoplasmic reticulum (ER) network has central roles in metabolism and cellular
organization. The ER undergoes dynamic alterations in morphology, molecular composition …
organization. The ER undergoes dynamic alterations in morphology, molecular composition …
[HTML][HTML] Emerging principles of selective ER autophagy
S Wilkinson - Journal of molecular biology, 2020 - Elsevier
The endoplasmic reticulum (ER) is a fundamental organelle in cellular metabolism and
signal transduction. It is subject to complex, dynamic sculpting of morphology and …
signal transduction. It is subject to complex, dynamic sculpting of morphology and …
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy
X Wang, X Jiang, B Li, J Zheng, J Guo, L Gao… - Journal of Cell …, 2023 - rupress.org
Macroautophagy (autophagy) utilizes a serial of receptors to specifically recognize and
degrade autophagy cargoes, including damaged organelles, to maintain cellular …
degrade autophagy cargoes, including damaged organelles, to maintain cellular …
Electrochemical biosensors for determination of colorectal tumor biomarkers
J Quinchia, D Echeverri, AF Cruz-Pacheco… - Micromachines, 2020 - mdpi.com
The accurate determination of specific tumor markers associated with cancer with non-
invasive or minimally invasive procedures is the most promising approach to improve the …
invasive or minimally invasive procedures is the most promising approach to improve the …
Critical roles of FAM134B in ER-phagy and diseases
J Mo, J Chen, B Zhang - Cell Death & Disease, 2020 - nature.com
Abstract FAM134B (also called JK-1, RETREG1), a member of the family with sequence
similarity 134, was originally discovered as an oncogene in esophageal squamous cell …
similarity 134, was originally discovered as an oncogene in esophageal squamous cell …
Autophagy modulators in cancer therapy
K Buzun, A Gornowicz, R Lesyk, K Bielawski… - International Journal of …, 2021 - mdpi.com
Autophagy is a process of self-degradation that plays an important role in removing
damaged proteins, organelles or cellular fragments from the cell. Under stressful conditions …
damaged proteins, organelles or cellular fragments from the cell. Under stressful conditions …
Different Roles of Apoptosis and Autophagy in the Development of Human Colorectal Cancer
G Orlandi, L Roncucci, G Carnevale… - International Journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) remains a major life-threatening malignancy, despite numerous
therapeutic and screening attempts. Apoptosis and autophagy are two processes that share …
therapeutic and screening attempts. Apoptosis and autophagy are two processes that share …
RETREG1 (FAM134B): A new player in human diseases: 15 years after the discovery in cancer
FAM134B (family with sequence similarity 134, member B)/RETREG1 and its functional
roles are relatively new in human diseases. This review aimed to summarize various …
roles are relatively new in human diseases. This review aimed to summarize various …