Curcumin formulations for better bioavailability: what we learned from clinical trials thus far?

M Hegde, S Girisa, B BharathwajChetty, R Vishwa… - ACS …, 2023 - ACS Publications
Curcumin has been credited with a wide spectrum of pharmacological properties for the
prevention and treatment of several chronic diseases such as arthritis, autoimmune …

Role of turmeric and curcumin in prevention and treatment of chronic diseases: Lessons learned from clinical trials

AB Kunnumakkara, M Hegde, D Parama… - ACS Pharmacology & …, 2023 - ACS Publications
Turmeric (Curcuma longa) has been used for thousands of years for the prevention and
treatment of various chronic diseases. Curcumin is just one of> 200 ingredients in turmeric …

Curcumin supplementation and human disease: a scoping review of clinical trials

TM Panknin, CL Howe, M Hauer… - International Journal of …, 2023 - mdpi.com
Medicinal properties of turmeric (Curcuma longa L.), a plant used for centuries as an anti-
inflammatory, are attributed to its polyphenolic curcuminoids, where curcumin predominates …

Natural products: Potential therapeutic agents to prevent skeletal muscle atrophy

A Yadav, SS Yadav, S Singh, R Dabur - European Journal of …, 2022 - Elsevier
The skeletal muscle (SkM) is the largest organ, which plays a vital role in controlling
musculature, locomotion, body heat regulation, physical strength, and metabolism of the …

Curcumin Targeting NF‐κB/Ubiquitin‐Proteasome‐System Axis Ameliorates Muscle Atrophy in Triple‐Negative Breast Cancer Cachexia Mice

J Zhang, J Zheng, H Chen, X Li, C Ye… - Mediators of …, 2022 - Wiley Online Library
Background. Curcumin is a polyphenol plant‐derived compound with anti‐inflammatory,
antioxidant stress, and anticancer properties that make it have the potential to treat cancer …

The role of mitochondria in the pathophysiology and treatment of common metabolic diseases in humans

A Georgiev, C Granata… - American Journal of …, 2022 - journals.physiology.org
Common metabolic diseases such as obesity, type 2 diabetes mellitus, and nonalcoholic
fatty liver disease significantly contribute to morbidity and mortality worldwide. They are …

Is curcumine useful in the treatment and prevention of the tendinopathy and myotendinous junction injury? A Scoping Review

A Córdova, F Drobnic, D Noriega-González… - Nutrients, 2023 - mdpi.com
Physical activity in general and sports in particular, is a mechanism that produces stress and
generates great force in the tendon and in the muscle-tendon unit, which increases the risk …

Mechanism of skeletal muscle atrophy after spinal cord injury: A narrative review

X Xu, Z Talifu, CJ Zhang, F Gao, H Ke, YZ Pan… - Frontiers in …, 2023 - frontiersin.org
Spinal cord injury leads to loss of innervation of skeletal muscle, decreased motor function,
and significantly reduced load on skeletal muscle, resulting in atrophy. Factors such as …

Evolution of natural product scaffolds as potential proteasome inhibitors in developing cancer therapeutics

RH Mir, PA Mir, J Uppal, A Chawla, M Patel, F Bardakci… - Metabolites, 2023 - mdpi.com
Homeostasis between protein synthesis and degradation is a critical biological function
involving a lot of precise and intricate regulatory systems. The ubiquitin-proteasome …

Polyphenols alleviate metabolic disorders: the role of ubiquitin-proteasome system

W Gu, G Wu, G Chen, X Meng, Z Xie, S Cai - Frontiers in Nutrition, 2024 - frontiersin.org
Metabolic disorders include obesity, nonalcoholic fatty liver disease, insulin resistance and
type 2 diabetes. It has become a major health issue around the world. Ubiquitin-proteasome …