Bone volume, microstructure and its material composition are maintained by bone
remodelling, a cellular activity carried out by bone multicellular units (BMUs). BMUs are …

Making use of the potential of calcium phosphates to host a variety of ions in their crystal
lattice, ion substitution of calcium phosphate bone cements has become the subject of …

Background A number of medications are approved for treatment of osteoporosis. As mode
of action usually is anti-catabolic/anti-resorptive or anabolic, it is of interest to know whether …

Periodontitis, a highly prevalent multicausal chronic inflammatory and destructive disease,
develops as a result of complex host‐parasite interactions. Dysbiotic bacterial biofilm in …

There has been growing recognition of the essential roles of citrate in biomechanical
properties of mineralized tissues, including teeth and bone. However, the sources of citrate …

Aims Deleterious effects of metabolic syndrome (MS) on bone are still controversial. In this
study we evaluated the effects of a fructose-induced MS, and/or an oral treatment with …

Longevity is increasing the burden of fractures. Although antiresorptive therapy slows
remodeling, it does not prevent or repair microstructural deterioration. The challenge is to …

Immobilization is known to cause a rapid bone loss due to increased osteoclastic bone
resorption and decreased osteoblastic bone formation. Zoledronate (Zln) is a potent anti …

Bone loss during advancing age is the net result of reduced modeling-based bone formation
upon the outer (periosteal) envelope and unbalanced remodeling by basic multicellular …

We investigated the combinatorial effects of whole-body vertical vibration (WBVV) with the
primarily osteoanabolic parathyroid hormone (PTH) and the mainly antiresorptive strontium …