Naringenin and naringin in cardiovascular disease prevention: A preclinical review

RH Moghaddam, Z Samimi, SZ Moradi, PJ Little… - European Journal of …, 2020 - Elsevier
Cardiovascular disease is an important cause for morbidity and mortality worldwide.
Flavonoids, such as naringin, and naringenin are important natural phytochemicals in the …

Combating oxidative stress disorders with citrus flavonoid: Naringenin

NH Zaidun, ZC Thent, A Abd Latiff - Life sciences, 2018 - Elsevier
The incidence of diseases related to oxidative stress disorders have been increased
dramatically. Alternatives medicine or the active compound extracted from the natural …

A recent review of citrus flavanone naringenin on metabolic diseases and its potential sources for high yield-production

N Karim, Z Jia, X Zheng, S Cui, W Chen - Trends in Food Science & …, 2018 - Elsevier
Background Metabolic syndromes are the multi-metabolic abnormality characterized by
hyperlipidemia, obesity, hyperglycemia, diabetes, hypertension, cardiovascular disease …

The role of necroptosis in cardiovascular disease

S Zhe-Wei, G Li-Sha, L Yue-Chun - Frontiers in pharmacology, 2018 - frontiersin.org
A newly discovered mechanism of cell death, programmed necrosis (necroptosis), combines
features of both necrosis and apoptosis. Necroptosis is tightly modulated by a series of …

Resveratrol-like compounds as SIRT1 activators

L Ciccone, E Piragine, S Brogi, C Camodeca… - International Journal of …, 2022 - mdpi.com
The sirtuin 1 (SIRT1) activator resveratrol has emerged as a promising candidate for the
prevention of vascular oxidative stress, which is a trigger for endothelial dysfunction …

Targeting the pathways of regulated necrosis: a potential strategy for alleviation of cardio-cerebrovascular injury

LQ Lu, J Tian, XJ Luo, J Peng - Cellular and Molecular Life Sciences, 2021 - Springer
Apoptosis, necrosis and autophagy-dependent cell death are the three major types of cell
death. Traditionally, necrosis is thought as a passive and unregulated form of cell death …

Modulation of hypercholesterolemia‐induced oxidative/nitrative stress in the heart

C Csonka, M Sárközy, M Pipicz, L Dux… - … medicine and cellular …, 2016 - Wiley Online Library
Hypercholesterolemia is a frequent metabolic disorder associated with increased risk for
cardiovascular morbidity and mortality. In addition to its well‐known proatherogenic effect …

Programmed necrosis in heart disease: molecular mechanisms and clinical implications

H Zhu, A Sun - Journal of molecular and cellular cardiology, 2018 - Elsevier
Programmed cell death plays an essential role in myocardial homeostasis and pathology.
Three distinct forms of programmed cell death have been identified, namely apoptosis …

Curcumin, naringenin and resveratrol from natural plant products hold promising solutions for modern world diseases–A recent review

R Thirumalaisamy, M Bhuvaneswari, S Haritha… - South African Journal of …, 2022 - Elsevier
In recent decades, our eating has become unhealthy, our lifestyle is sedentary, working is
stressful and our living environment is also polluted causing number of diseases which …

Naringenin improves mitochondrial function and reduces cardiac damage following ischemia-reperfusion injury: the role of the AMPK-SIRT3 signaling pathway

LM Yu, X Dong, XD Xue, J Zhang, Z Li, HJ Wu… - Food & function, 2019 - pubs.rsc.org
Mitochondrial dysfunction contributed greatly to myocardial ischemia-reperfusion (MI/R)-
induced cardiomyocyte apoptosis. Naringenin is a flavonoid exhibiting potential protective …