Impacts of genome-wide analyses on our understanding of human herpesvirus diversity and evolution

DW Renner, ML Szpara - Journal of virology, 2018 - Am Soc Microbiol
Until fairly recently, genome-wide evolutionary dynamics and within-host diversity were
more commonly examined in the context of small viruses than in the context of large double …

Within-host viral diversity: a window into viral evolution

AS Lauring - Annual Review of Virology, 2020 - annualreviews.org
The evolutionary dynamics of a virus can differ within hosts and across populations. Studies
of within-host evolution provide an important link between experimental studies of virus …

Natural history of congenital cytomegalovirus infection in highly seropositive populations

MM Mussi-Pinhata, AY Yamamoto - The Journal of infectious …, 2020 - academic.oup.com
Maternal preconceptional cytomegalovirus (CMV) immunity does not protect the fetus from
acquiring congenital CMV infection (cCMV). Nonprimary infections due to recurrence of …

Developing an appropriate evolutionary baseline model for the study of SARS-CoV-2 patient samples

JW Terbot, P Johri, SW Liphardt, V Soni… - PLoS …, 2023 - journals.plos.org
Over the past 3 years, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
has spread through human populations in several waves, resulting in a global health crisis …

Developing an appropriate evolutionary baseline model for the study of human cytomegalovirus

AA Howell, JW Terbot, V Soni, P Johri… - Genome biology and …, 2023 - academic.oup.com
Human cytomegalovirus (HCMV) represents a major threat to human health, contributing to
both birth defects in neonates as well as organ transplant failure and opportunistic infections …

Human cytomegalovirus infection in women with preexisting immunity: sources of infection and mechanisms of infection in the presence of antiviral immunity

WJ Britt - The Journal of Infectious Diseases, 2020 - academic.oup.com
Human cytomegalovirus (HCMV) infection remains an important cause of
neurodevelopmental sequelae in infants infected in utero. Unique to the natural history of …

Mixed cytomegalovirus genotypes in HIV-positive mothers show compartmentalization and distinct patterns of transmission to infants

J Pang, JA Slyker, S Roy, J Bryant, C Atkinson, J Cudini… - Elife, 2020 - elifesciences.org
Cytomegalovirus (CMV) is the commonest cause of congenital infection and particularly so
among infants born to HIV-infected women. Studies of congenital CMV infection (cCMVi) …

Protective effect of pre-existing natural immunity in a nonhuman primate reinfection model of congenital cytomegalovirus infection

MJ Moström, S Yu, D Tran, FM Saccoccio… - PLoS …, 2023 - journals.plos.org
Congenital cytomegalovirus (cCMV) is the leading infectious cause of neurologic defects in
newborns with particularly severe sequelae in the setting of primary CMV infection in the first …

Characterization of a live-attenuated HCMV-based vaccine platform

P Caposio, S van den Worm, L Crawford, W Perez… - Scientific reports, 2019 - nature.com
Vaccines based on cytomegalovirus (CMV) demonstrate protection in animal models of
infectious disease and cancer. Vaccine efficacy is associated with the ability of CMV to elicit …

Common polymorphisms in the glycoproteins of human cytomegalovirus and associated strain-specific immunity

HY Wang, SM Valencia, SP Pfeifer, JD Jensen… - Viruses, 2021 - mdpi.com
Human cytomegalovirus (HCMV), one of the most prevalent viruses across the globe, is a
common cause of morbidity and mortality for immunocompromised individuals. Recent …