Clostridioides difficile is the most common cause of nosocomial antibiotic-associated
diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …

Cellular mechanical properties play an integral role in bacterial survival and adaptation.
Historically, the bacterial cell wall and, in particular, the layer of polymeric material called the …

The cell wall of Gram-positive bacteria is a complex assemblage of glycopolymers and
proteins. It consists of a thick peptidoglycan sacculus that surrounds the cytoplasmic …

The outer surface of many archaea and bacteria is coated with a proteinaceous surface
layer (known as an S-layer), which is formed by the self-assembly of monomeric proteins …

Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

The peptidoglycan biosynthetic pathway is a critical process in the bacterial cell and is
exploited as a target for the design of antibiotics. This pathway culminates in the production …

Many bacteria and archaea possess a two-dimensional protein array, or S-layer, that covers
the cell surface and plays crucial roles in cell physiology. Here, we report the crystal …

The peptidoglycan (PG) cell wall is an essential polymer for the shape and viability of
bacteria. Its protective role is in great part provided by its mesh‐like character. Therefore, PG …

Clostridium difficile infection is the leading cause of antibiotic-and healthcare-associated
diarrhea, and its containment and treatment imposes a significant financial burden …

Leveraging systems biology approaches, we illustrate how metabolically distinct species of
Clostridia protect against or worsen Clostridioides difficile infection in mice by modulating …