Toll‐like receptors (TLRs): structure, functions, signaling, and role of their polymorphisms in colorectal cancer susceptibility
AS Sameer, S Nissar - BioMed Research International, 2021 - Wiley Online Library
Toll‐like receptors (TLRs) are the important mediators of inflammatory pathways in the gut
which play a major role in mediating the immune responses towards a wide variety of …
which play a major role in mediating the immune responses towards a wide variety of …
KRAS: From undruggable to a druggable Cancer Target
D Uprety, AA Adjei - Cancer treatment reviews, 2020 - Elsevier
RAS is the most frequently mutated oncogene in human cancers, with mutations in about
30% of all cancers. RAS exists in three different isoforms (K-RAS, H-RAS and N-RAS) with …
30% of all cancers. RAS exists in three different isoforms (K-RAS, H-RAS and N-RAS) with …
T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing
H Chi, S Zhao, J Yang, X Gao, G Peng… - Frontiers in …, 2023 - frontiersin.org
Background Hepatocellular carcinoma (HCC), the third most prevalent cause of cancer-
related death, is a frequent primary liver cancer with a high rate of morbidity and mortality. T …
related death, is a frequent primary liver cancer with a high rate of morbidity and mortality. T …
Withania Somnifera (Ashwagandha) and Withaferin A: Potential in Integrative Oncology
Ashwagandha (Withania Somnifera, WS), belonging to the family Solanaceae, is an
Ayurvedic herb known worldwide for its numerous beneficial health activities since ancient …
Ayurvedic herb known worldwide for its numerous beneficial health activities since ancient …
Recent insights into nanotechnology in colorectal cancer
AAZ Dezfuli, M Abu-Elghait, SS Salem - Applied Biochemistry and …, 2024 - Springer
Colorectal cancer (CRC) is the third cancer among the known causes of cancer that impact
people. Although CRC drug options are imperfect, primary detection of CRC can play a key …
people. Although CRC drug options are imperfect, primary detection of CRC can play a key …
[HTML][HTML] Colorectal cancer liver metastasis: evolving paradigms and future directions
In patients with colorectal cancer (CRC) that metastasizes to the liver, there are several key
goals for improving outcomes including early detection, effective prognostic indicators of …
goals for improving outcomes including early detection, effective prognostic indicators of …
[HTML][HTML] Microsatellite instability in colorectal cancer
JN Nojadeh, SB Sharif, E Sakhinia - EXCLI journal, 2018 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a heterogeneous disease that is caused by the interaction of
genetic and environmental factors. Although it is one of the most common cancers …
genetic and environmental factors. Although it is one of the most common cancers …
Colorectal cancer in the young
SG Patel, DJ Ahnen - Current gastroenterology reports, 2018 - Springer
Abstract Purpose of Review Colorectal cancer incidence has been rapidly rising in those
under the age of 50 over the last 20 years. This paper will review the epidemiology …
under the age of 50 over the last 20 years. This paper will review the epidemiology …
The rising incidence of younger patients with colorectal cancer: questions about screening, biology, and treatment
Opinion statement Colorectal cancer (CRC) is the third leading cancer diagnosed globally
and an important cause of cancer-related mortality. Of interest, while we have witnessed a …
and an important cause of cancer-related mortality. Of interest, while we have witnessed a …
Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid
Cannabigerol (CBG) is a safe non-psychotropic Cannabis-derived cannabinoid (CB), which
interacts with specific targets involved in carcinogenesis. Specifically, CBG potently blocks …
interacts with specific targets involved in carcinogenesis. Specifically, CBG potently blocks …