Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability
worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information …

Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …

Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …

Ischemic stroke is the leading cause of immortal disability and death worldwide. For
treatment in the acute phase, it is necessary to control excessive reactive oxygen species …

The nervous and immune systems control whole-body homeostasis and respond to various
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …

Following a cerebral ischemic event, substantial alterations in both cellular and molecular
activities occur due to ischemia-induced cerebral pathology. Mounting evidence indicates …

Accumulation of amyloid beta protein (Aβ) in brain vessels damages blood brain barrier
(BBB) integrity in cerebral amyloid angiopathy (CAA). Macrophage lineage cells scavenge …

Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein‐1
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …

Immunomodulation holds therapeutic promise against brain injuries, but leveraging this
approach requires a precise understanding of mechanisms. We report that CD8+ CD122+ …

Background Ischemic stroke is a medical emergency that primarily affects the elderly. A
complex immune response in the post-stroke brain constitutes a key component of stroke …