Why Y matters? The implication of loss of Y chromosome in blood and cancer
Y Wang, S Sano - Cancer Science, 2024 - Wiley Online Library
Hematopoietic mosaic loss of Y chromosome (mLOY) has emerged as a potential male‐
specific accelerator of biological aging, increasing the risk of various age‐related diseases …
specific accelerator of biological aging, increasing the risk of various age‐related diseases …
Loss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases
M Wójcik, U Juhas, E Mohammadi, J Mattisson… - Scientific Reports, 2024 - nature.com
Male sex is a risk factor for colorectal cancer (CRC) with higher illness burden and earlier
onset. Thus, we hypothesized that loss of chromosome Y (LOY) in the tumor micro …
onset. Thus, we hypothesized that loss of chromosome Y (LOY) in the tumor micro …
Loss of Y Chromosome and Cardiovascular Events in Chronic Kidney Disease
M Weyrich, S Cremer, M Gerster, T Sarakpi, T Rasper… - Circulation, 2024 - ahajournals.org
BACKGROUND: Chronic kidney disease represents one of the strongest risk factors for
cardiovascular diseases, and particularly for heart failure. Despite improved pharmaceutical …
cardiovascular diseases, and particularly for heart failure. Despite improved pharmaceutical …