[HTML][HTML] Carbohydrate-based drugs launched during 2000− 2021

X Cao, X Du, H Jiao, Q An, R Chen, P Fang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

Next generation of fluorine-containing pharmaceuticals, compounds currently in phase II–III clinical trials of major pharmaceutical companies: new structural trends …

Y Zhou, J Wang, Z Gu, S Wang, W Zhu… - Chemical …, 2016 - ACS Publications
Fluoroorganic chemistry has become essential in the evolution of many different but
interconnected research fields. These include the development of new materials with a …

Association of SGLT2 inhibitors with arrhythmias and sudden cardiac death in patients with type 2 diabetes or heart failure: a meta-analysis of 34 randomized …

GC Fernandes, A Fernandes, R Cardoso, J Penalver… - Heart Rhythm, 2021 - Elsevier
Background Sodium-glucose cotransporter 2 inhibitors (SGLT2is) reduce hospitalizations
and death from heart failure (HF), but their effect on arrhythmia expression has been poorly …

Anti-diabetic drugs and weight loss in patients with type 2 diabetes

E Lazzaroni, MB Nasr, C Loretelli, I Pastore… - Pharmacological …, 2021 - Elsevier
Introduction Obesity is frequently a comorbidity of type 2 diabetes. Even modest weight loss
can significantly improve glucose homeostasis and lessen cardiometabolic risk factors in …

Beneficial effects of sodium–glucose cotransporter 2 inhibitors for preservation of pancreatic β‐cell function and reduction of insulin resistance: 钠‐葡萄糖共转运体2 …

H Kaneto, A Obata, T Kimura, M Shimoda… - Journal of …, 2017 - Wiley Online Library
2 型糖尿病的特征是在不同的胰岛素靶组织如肝脏, 脂肪组织与骨骼肌中发生的胰岛素抵抗以及
来自胰腺β 细胞的胰岛素分泌量不足. 钠‐葡萄糖共转运体2 (SGLT2) 抑制剂是一种最新研制的 …

[HTML][HTML] RSSDI-ESI Clinical Practice Recommendations for the Management of Type 2 Diabetes Mellitus 2020Table. No title available.

R Chawla, SV Madhu, BM Makkar… - Indian journal of …, 2020 - journals.lww.com
Guidelines RSSDI-ESI Clinical Practice Recommendations for the Management of Type 2
Diabetes Mellitus 2020Table. No title available.

Effects of sodium-glucose cotransporter-2 inhibitors on cardiovascular events, death, and major safety outcomes in adults with type 2 diabetes: a systematic review …

JHY Wu, C Foote, J Blomster, T Toyama… - The lancet Diabetes & …, 2016 - thelancet.com
Background In patients with type 2 diabetes, sodium-glucose cotransporter-2 (SGLT2)
inhibitors are known to reduce glucose concentrations, blood pressure, and weight, but to …

Novel noninvasive approaches to the treatment of obesity: from pharmacotherapy to gene therapy

AM Angelidi, MJ Belanger, A Kokkinos… - Endocrine …, 2022 - academic.oup.com
Recent insights into the pathophysiologic underlying mechanisms of obesity have led to the
discovery of several promising drug targets and novel therapeutic strategies to address the …

Effect of sodium‐glucose cotransport‐2 inhibitors on blood pressure in people with type 2 diabetes mellitus: a systematic review and meta‐analysis of 43 randomized …

M Mazidi, P Rezaie, HK Gao… - Journal of the American …, 2017 - Am Heart Assoc
Background The sodium‐glucose cotransporter 2 (SGLT 2) inhibitors are a class of oral
hypoglycemic agents. We undertake a systematic review and meta‐analysis of prospective …

Effects of canagliflozin on fracture risk in patients with type 2 diabetes mellitus

NB Watts, JP Bilezikian, K Usiskin… - The Journal of …, 2016 - academic.oup.com
Context: Canagliflozin is a sodium glucose cotransporter 2 inhibitor developed to treat type 2
diabetes mellitus (T2DM). Objective: The purpose of this study was to describe the effects of …