Making waves: New developments in toxicology with the zebrafish

KA Horzmann, JL Freeman - Toxicological Sciences, 2018 - academic.oup.com
The laboratory zebrafish (Danio rerio) is now an accepted model in toxicologic research.
The zebrafish model fills a niche between in vitro models and mammalian biomedical …

Zebrafish behavior: opportunities and challenges

MB Orger, GG de Polavieja - Annual review of neuroscience, 2017 - annualreviews.org
A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

Comparative analyses of zebrafish anxiety-like behavior using conflict-based novelty tests

EV Kysil, DA Meshalkina, EE Frick, DJ Echevarria… - Zebrafish, 2017 - liebertpub.com
Modeling of stress and anxiety in adult zebrafish (Danio rerio) is increasingly utilized in
neuroscience research and central nervous system (CNS) drug discovery. Representing the …

Zebrafish models in neuropsychopharmacology and CNS drug discovery

KM Khan, AD Collier, DA Meshalkina… - British journal of …, 2017 - Wiley Online Library
Despite the high prevalence of neuropsychiatric disorders, their aetiology and molecular
mechanisms remain poorly understood. The zebrafish (Danio rerio) is increasingly utilized …

[HTML][HTML] Zebrafish get connected: investigating neurotransmission targets and alterations in chemical toxicity

KA Horzmann, JL Freeman - Toxics, 2016 - mdpi.com
Neurotransmission is the basis of neuronal communication and is critical for normal brain
development, behavior, learning, and memory. Exposure to drugs and chemicals can alter …

Zebrafish models of autism spectrum disorder

DA Meshalkina, MN Kizlyk, EV Kysil, AD Collier… - Experimental …, 2018 - Elsevier
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by motor, social and cognitive deficits that develop early during childhood. The …

Fish behavior: A promising model for aquatic toxicology research

X Hong, J Zha - Science of the total environment, 2019 - Elsevier
Fish behaviors have great potential as models for the study of pharmacology, genetics, and
neuroscience. Zebrafish (Danio rerio), Japanese medaka (Oryzias latipes) and Chinese rare …

Neurological impairment is crucial for tire rubber-derived contaminant 6PPDQ-induced acute toxicity to rainbow trout

XL Liao, ZF Chen, SP Ou, QY Liu, SH Lin, JM Zhou… - Science Bulletin, 2024 - Elsevier
Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine quinone (6PPDQ) has
attracted significant attention due to its highly acute lethality to sensitive salmonids …

Zebrafish neurobehavioral phenomics for aquatic neuropharmacology and toxicology research

AV Kalueff, DJ Echevarria, S Homechaudhuri… - Aquatic Toxicology, 2016 - Elsevier
Zebrafish (Danio rerio) are rapidly emerging as an important model organism for aquatic
neuropharmacology and toxicology research. The behavioral/phenotypic complexity of …

Antagonistic effects in zebrafish (Danio rerio) behavior and oxidative stress induced by toxic metals and deltamethrin acute exposure

R Jijie, G Solcan, M Nicoara, D Micu… - Science of the total …, 2020 - Elsevier
In natural environments, the aquatic organisms are exposed to complex mixtures of
chemicals which may originate from natural sources or from anthropogenic activities. In this …