PEG-PCL-based nanomedicines: A biodegradable drug delivery system and its application

P Grossen, D Witzigmann, S Sieber… - Journal of Controlled …, 2017 - Elsevier
The lack of efficient therapeutic options for many severe disorders including cancer spurs
demand for improved drug delivery technologies. Nanoscale drug delivery systems based …

Molecular interactions in organic nanoparticles for phototheranostic applications

KK Ng, G Zheng - Chemical reviews, 2015 - ACS Publications
Optical and photonic technologies play an important role in human progress. The bending of
light to our will has not only enabled our biological self-discovery, but has also allowed us to …

Polymeric micelle stability

SC Owen, DPY Chan, MS Shoichet - Nano today, 2012 - Elsevier
Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-
scale aggregates form spontaneously in aqueous solution and can be used to overcome …

Multi-stimuli responsive polymers–the all-in-one talents

P Schattling, FD Jochum, P Theato - Polymer Chemistry, 2014 - pubs.rsc.org
Stimuli-responsive polymers have gained increasing attention, which is attributed to the
manifold applications they can be used for. Several years' intensive research was invested …

Nanonization strategies for poorly water-soluble drugs

H Chen, C Khemtong, X Yang, X Chang, J Gao - Drug discovery today, 2011 - Elsevier
Poor water solubility for many drugs and drug candidates remains a major obstacle to their
development and clinical application. Conventional formulations to improve solubility suffer …

PEG–PLGA copolymers: Their structure and structure-influenced drug delivery applications

K Zhang, X Tang, J Zhang, W Lu, X Lin, Y Zhang… - Journal of Controlled …, 2014 - Elsevier
In the paper, we begin by describing polyethylene glycol–poly lactic acid-co-glycolic acid
(PEG–PLGA) which was chosen as a typical model copolymer for the construction of nano …

Applications of polymer micelles for imaging and drug delivery

S Movassaghian, OM Merkel… - Wiley Interdisciplinary …, 2015 - Wiley Online Library
Polymeric micelles, self‐assembling nano‐constructs of amphiphilic copolymers, are widely
considered as convenient nano‐carriers for a variety of applications, such as diagnostic …

Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers

ZL Tyrrell, Y Shen, M Radosz - Progress in Polymer Science, 2010 - Elsevier
Micelles formed through the self-assembly of block copolymers have been widely used to
encapsulate highly hydrophobic drugs to increase their effective solubility. However, this …

NLRP3 inflammasome-targeting nanomicelles for preventing ischemia–reperfusion-induced inflammatory injury

R Prakash, A Vyawahare, R Sakla, N Kumari… - ACS …, 2023 - ACS Publications
Ischemia–reperfusion (I/R) injury is a disease process that affects several vital organs. There
is widespread agreement that the NLRP3 inflammasome pathway plays a crucial role in the …

Polymeric micelles: authoritative aspects for drug delivery

SS Kulthe, YM Choudhari, NN Inamdar… - Designed Monomers …, 2012 - Taylor & Francis
The generation of supramolecular architectures with well-defined structures and
functionalities is recently garnering attraction. Self-assemblage of amphiphilic polymers …