Tyrosine conjugation methods for protein labelling
D Alvarez Dorta, D Deniaud, M Mével… - … –A European Journal, 2020 - Wiley Online Library
Over the last two decades, the development of chemical biology and the need for more
defined protein conjugates have fostered active research on new bioconjugation …
defined protein conjugates have fostered active research on new bioconjugation …
Research progress on chemical modifications of tyrosine residues in peptides and proteins
W Zeng, J Xue, H Geng, X Liu, J Yang… - Biotechnology and …, 2024 - Wiley Online Library
The chemical modifications (CMs) of protein is an important technique in chemical biology,
protein‐based therapy, and material science. In recent years, there has been rapid …
protein‐based therapy, and material science. In recent years, there has been rapid …
A chemoselective rapid azo-coupling reaction (CRACR) for unclickable bioconjugation
Chemoselective modification of complex biomolecules has become a cornerstone of
chemical biology. Despite the exciting developments of the past two decades, the demand …
chemical biology. Despite the exciting developments of the past two decades, the demand …
Modifications of amino acids using arenediazonium salts
S Sengupta, S Chandrasekaran - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
Aryl transfer reactions from arenediazonium salts have started to make their impact in
chemical biology with initial forays in the arena of arylative modifications and bio …
chemical biology with initial forays in the arena of arylative modifications and bio …
Protein modification via mild photochemical isomerization of triazenes to release aryl diazonium ions
GJ Davis, JA Townsend, MG Morrow… - Bioconjugate …, 2021 - ACS Publications
This work describes the development of phenyl diazenyl piperidine triazene derivatives that
can be activated to release aryl diazonium ions for labeling of proteins using light. These …
can be activated to release aryl diazonium ions for labeling of proteins using light. These …
Virus-based supramolecular structure and materials: Concept and prospects
C Hou, H Xu, X Jiang, Y Li, S Deng… - ACS Applied Bio …, 2021 - ACS Publications
Rodlike and spherelike viruses are various monodisperse nanoparticles that can display
small molecules or polymers with unique distribution following chemical modifications …
small molecules or polymers with unique distribution following chemical modifications …
Copper-free click enabled triazabutadiene for bioorthogonal protein functionalization
AN Wijetunge, GJ Davis, M Shadmehr… - Bioconjugate …, 2021 - ACS Publications
Aryl diazonium ions have long been used in bioconjugation due to their reactivity toward
electron-rich aryl residues, such as tyrosine. However, their utility in biological systems has …
electron-rich aryl residues, such as tyrosine. However, their utility in biological systems has …
Selective Triazenation Reaction (STaR) of secondary amines for tagging monomethyl lysine post‐translational modifications
Lysine monomethylation (Kme) is an impactful post‐translational modification (PTM)
responsible for regulating biological processes and implicated in diseases, thus there is …
responsible for regulating biological processes and implicated in diseases, thus there is …
Site-directed chemically-modified magnetic enzymes: fabrication, improvements, biotechnological applications and future prospects
Numerous enzymes of biotechnological importance have been immobilized on magnetic
nanoparticles (MNP) via random multipoint attachment, resulting in a heterogeneous protein …
nanoparticles (MNP) via random multipoint attachment, resulting in a heterogeneous protein …
A Novel Bifunctional Chelating Agent for Tyrosine-Specific Radiolabeling of Peptides and Proteins
D Nakano, H Watanabe, S Kosuke… - Bioconjugate Chemistry, 2024 - ACS Publications
Site-specific radiolabeling is utilized for the development of antibody-or peptide-based
radiotheranostic agents. Although tyrosine can be exploited as one of the target residues for …
radiotheranostic agents. Although tyrosine can be exploited as one of the target residues for …