Coumarins belong to the benzopyrone family commonly found in many medicinal plants.
Natural coumarins demonstrated a wide spectrum of pharmacological activities, including …

A hypercoagulable or prothrombotic state of malignancy occurs due to the ability of tumor
cells to activate the coagulation system. It has been estimated that hypercoagulation …

Background Little is known about the prognosis of cancer discovered during or after an
episode of venous thromboembolism. Methods We linked the Danish National Registry of …

Background Venous thromboembolism (VTE) often complicates the clinical course of
cancer. The risk is further increased by chemotherapy, but the trade‐off between safety and …

Patients receiving chemotherapy for metastatic breast cancer are at high risk of
thromboembolic disease. Long-term oral anticoagulant therapy is needed but increases the …

Purpose Experimental studies and indirect clinical evidence suggest that low molecular
weight heparins may have antineoplastic effects. We investigated the influence of a low …

Background The length of time after an episode of venous thromboembolism during which
the risk of newly diagnosed cancer is increased is not known, and whether vitamin K …

An association between cancer and the coagulation system was suggested by Trousseau
more than a century ago and initial reports of fibrin deposition in the stroma of solid tumors …

Metastasis involves several distinct steps, including one in which the tumor cell, after entry
into the bloodstream, comes to rest in a capillary located at the distant site where a …

BACKGROUND. Preclinical evidence suggests that anticoagulants, in particular the low‐
molecular‐weight heparins (LMWH), exert an antitumor effect, whereas clinical trials have …