Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …

Symptoms of cognitive dysfunction like memory loss, poor concentration, impaired learning
and executive functions are characteristic features of both schizophrenia and Alzheimer's …

Serotonin [5-hydroxytryptamine (5-HT)] is a multifunctional neurotransmitter innervating
cortical and limbic areas involved in cognition and emotional regulation. Dysregulation of …

Abstract Behavioral and Psychological Symptoms of Dementia (BPSD), present in almost
90% of patients with Alzheimer's Disease (AD), cause extensive impairment leading to …

Since its discovery in the 1940s in serum, the mammalian intestinal mucosa, and in the
central nervous system, serotonin (5-HT) has been shown to be involved in virtually all …

A concise review covering updated presence and role of 2-phenethylamines in medicinal
chemistry is presented. Open-chain, flexible alicyclic amine derivatives of this motif are …

Abstract Serotonin, or 5-hydroxytryptamine (5-HT), is found to be involved in many
physiological or pathophysiological processes including cognitive function. Seven distinct …

Pharmacological and genetic tools targeting the 5-hydroxytryptamine (5-HT) 7 receptor in
preclinical animal models have implicated this receptor in diverse (patho) physiological …

Like most neurotransmitters, serotonin possesses a simple structure. However, the
pharmacological consequences are more complex and diverse. Serotonin is involved in …

Abstract The 5-HT 7 (5-hydroxytryptamine 7, serotonin 7) receptor is one of the most recently
identified members of the serotonin receptor family. Pharmacological tools, including …