New insights into the interplay between long non‐coding RNAs and RNA‐binding proteins in cancer

ZT Yao, YM Yang, MM Sun, Y He, L Liao… - Cancer …, 2022 - Wiley Online Library
With the development of proteomics and epigenetics, a large number of RNA‐binding
proteins (RBPs) have been discovered in recent years, and the interaction between long …

[HTML][HTML] Molecular landscape of LncRNAs in bladder cancer: from drug resistance to novel LncRNA-based therapeutic strategies

A Mehmandar-Oskuie, K Jahankhani… - Biomedicine & …, 2023 - Elsevier
Bladder cancer (BC) is a common and serious type of cancer that ranks among the top ten
most prevalent malignancies worldwide. Due to the high occurrence rate of BC, the …

LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer

W Luo, J Wang, W Xu, C Ma, F Wan, Y Huang… - Cell death & …, 2021 - nature.com
Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and
development in bladder cancer. However, the underlying molecular mechanisms remain …

NSUN2‐mediated m5C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression

S Zuo, L Li, X Wen, X Gu, A Zhuang, R Li… - Clinical and …, 2023 - Wiley Online Library
Background The precise temporal and spatial regulation of N5‐methylcytosine (m5C) RNA
modification plays essential roles in RNA metabolism, and is necessary for the maintenance …

Long non-coding RNAs as new players in bladder cancer: Lessons from pre-clinical and clinical studies

S Mirzaei, MDA Paskeh, F Hashemi, A Zabolian… - Life Sciences, 2022 - Elsevier
The clinical management of bladder cancer (BC) has become an increasing challenge due
to high incidence rate of BC, malignant behavior of cancer cells and drug resistance. The …

IGF2BP3 enhances the mRNA stability of E2F3 by interacting with LINC00958 to promote endometrial carcinoma progression

C Wang, F Kong, J Ma, J Miao, P Su, H Yang, Q Li… - Cell death …, 2022 - nature.com
Long noncoding RNAs (lncRNAs) play important regulatory roles in a variety of pathological
processes involving cancer. However, the exact molecular mechanisms of lncRNA …

Regulation of epigenetic homeostasis in uveal melanoma and retinoblastoma

P Chai, R Jia, Y Li, C Zhou, X Gu, L Yang, H Shi… - Progress in retinal and …, 2022 - Elsevier
Uveal melanoma (UM) and retinoblastoma (RB), which cause blindness and even death,
are the most frequently observed primary intraocular malignancies in adults and children …

Upregulation of LINC00501 by H3K27 acetylation facilitates gastric cancer metastasis through activating epithelial‐mesenchymal transition and angiogenesis

R Dou, L Han, C Yang, Y Fang, J Zheng… - Clinical and …, 2023 - Wiley Online Library
Background The molecular mechanism of the significant role of long noncoding RNAs
(lncRNAs) in the progression and metastasis of gastric cancer (GC) remains largely elusive …

LCAT1 is an oncogenic LncRNA by stabilizing the IGF2BP2-CDC6 axis

J Yang, X Qian, Q Qiu, L Xu, M Pan, J Li, J Ren… - Cell Death & …, 2022 - nature.com
Long non-coding RNAs (lncRNAs) is known to play vital roles in modulating tumorigenesis.
We previously reported that LCAT1, a novel lncRNA, promotes the growth and metastasis of …

Low Glucose–Induced Overexpression of HOXC-AS3 Promotes Metabolic Reprogramming of Breast Cancer

W Zhu, X Chen, X Guo, H Liu, R Ma, Y Wang, Y Liang… - Cancer Research, 2022 - AACR
Breast cancer is the most common malignancy in women worldwide. However, the
mechanisms underlying breast cancer energy metabolism and progression remain obscure …