Magnetite nanoparticles in magnetic hyperthermia and cancer therapies: Challenges and perspectives

A Włodarczyk, S Gorgoń, A Radoń, K Bajdak-Rusinek - Nanomaterials, 2022 - mdpi.com
Until now, strategies used to treat cancer are imperfect, and this generates the need to
search for better and safer solutions. The biggest issue is the lack of selective interaction …

New drug delivery systems developed for brain targeting

SU Rawal, BM Patel, MM Patel - Drugs, 2022 - Springer
The blood-brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSF) are two of
the most complex and sophisticated concierges that defend the central nervous system …

Magnetic Nanocomposites and Imprinted Polymers for Biomedical Applications of Nucleic Acids

V Popova, E Dmitrienko, A Chubarov - Magnetochemistry, 2022 - mdpi.com
Magnetic nanocomposites (MNCs) combine the features of magnetic nanoparticles and a
second material, which provide distinct physical, chemical, and biological properties. The …

[HTML][HTML] Nanomaterial-assisted CRISPR gene-engineering–A hallmark for triple-negative breast cancer therapeutics advancement

J Farheen, NS Hosmane, R Zhao, Q Zhao, MZ Iqbal… - Materials Today Bio, 2022 - Elsevier
Triple-negative breast cancer (TNBC) is the most violent class of tumor and accounts for 20–
24% of total breast carcinoma, in which frequently rare mutation occurs in high frequency …

The Yin and Yang of epigenetics in the field of nanoparticles

E Musolino, C Pagiatakis, S Serio, M Borgese… - Nanoscale …, 2022 - pubs.rsc.org
Nanoparticles (NPs) have become a very exciting research avenue, with multitudinous
applications in various fields, including the biomedical one, whereby they have been …

Magnetically-assisted viral transduction (magnetofection) medical applications: An update

B Azadpour, N Aharipour, A Paryab, H Omid… - Biomaterials …, 2023 - Elsevier
Gene therapy involves replacing a faulty gene or adding a new gene inside the body's cells
to cure disease or improve the body's ability to fight disease. Its popularity is evident from …

[HTML][HTML] Nanocarriers for delivery of siRNA as gene silencing mediator

A Morales-Becerril, L Aranda-Lara, K Isaac-Olivé… - EXCLI …, 2022 - ncbi.nlm.nih.gov
The term nanocarrier refers to sub-micrometric particles of less than 100 nm, designed to
transport, distribute, and release nanotechnology-based drug delivery systems. siRNA …

Research progress on nanoparticles-based CRISPR/Cas9 system for targeted therapy of tumors

D Nie, T Guo, M Yue, W Li, X Zong, Y Zhu, J Huang… - Biomolecules, 2022 - mdpi.com
Cancer is a genetic mutation disease that seriously endangers the health and life of all
human beings. As one of the most amazing academic achievements in the past decade …

Mesenchymal stem cells engineered by nonviral vectors: A powerful tool in cancer gene therapy

Y Ding, C Wang, Z Sun, Y Wu, W You, Z Mao, W Wang - Pharmaceutics, 2021 - mdpi.com
Due to their “tumor homing” and “immune privilege” characteristics, the use of mesenchymal
stem cells (MSCs) has been proposed as a novel tool against cancer. MSCs are genetically …

Banana fruit (Musa sp.) DNA-magnetite nanoparticles: Synthesis, characterization, and biocompatibility assays on normal and cancerous cells

D Arregui-Almeida, M Coronel, K Analuisa… - Plos one, 2024 - journals.plos.org
Magnet-mediated gene therapy has gained considerable interest from researchers as a
novel alternative for treating genetic disorders, particularly through the use of …