The placenta is a transitory organ, located between the mother and the foetus, which
supports intrauterine life. This organ has nutritional, endocrine and immunologic functions to …

Methods to evaluate maternal-fetal transport across the placental barrier have generally
involved clinical observations after-the-fact, ex vivo perfused placenta studies, or in vitro …

The placenta is crucial for life. It is an ephemeral but complex organ acting as the barrier
interface between maternal and fetal circulations, providing exchange of gases, nutrients …

Fetal growth restriction (FGR) affects 5–10% of pregnancies, leading to clinically significant
fetal morbidity and mortality. FGR placentae frequently exhibit poor vascular branching, but …

Objectives To determine whether placental vascular pathology and impaired placental
exchange due to maturational defects are involved in the etiology of spontaneous preterm …

The placenta provides the vital nutrients and removal of waste products required for fetal
growth and development. Understanding and quantifying the differences in structure and …

Multi-scale structural assessment of biological soft tissue is challenging but essential to gain
insight into structure–function relationships of tissue/organ. Using the human placenta as an …

Objectives Spontaneous preterm labor is an obstetrical syndrome accounting for
approximately 65–70% of preterm births, the latter being the most frequent cause of …

Across mammalian species, solute exchange takes place in complex microvascular
networks. In the human placenta, the primary exchange units are terminal villi that contain …

In recent years, biological imaging techniques have advanced significantly and it is now
possible to digitally reconstruct microvascular network structures in detail, identifying the …