Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as
effectors of allergy. It has been only in the past two decades that mast cells have gained …

Mast cells are well known for their role in allergic and anaphylactic reactions, as well as their
involvement in acquired and innate immunity. Increasing evidence now implicates mast cells …

Neutrophil recruitment is an important early step in controlling tissue infections or injury.
Here, we report that this influx depends on both tissue-resident mast cells and …

Although mast cells were discovered more than a century ago, their functions beyond their
role in allergic responses remained elusive until recently. However, there is a growing …

Mast cells (MC s) are innate immune cells that are scattered in tissues throughout the
organism being particularly abundant at sites exposed to the environment such as the skin …

In addition to the well known role of mast cells in immunity to multi-cellular parasites and in
the pathogenesis of allergy and asthma, the importance of mast cells in the immune defense …

Mast cells are well known for their involvement in allergic and anaphylactic reactions, during
which immunoglobulin E (IgE) receptor (FcɛRI) aggregation leads to exocytosis of the …

Anaphylaxis is the systemic and most severe presentation of type I allergy. A number of
conditions were identified that modulate the onset of anaphylaxis such as co‐or …

Mast cells are multifunctional cells that initiate not only IgE-dependent allergic diseases but
also play a fundamental role in innate and adaptive immune responses to microbial …

Mast cells are crucial effector cells in allergic reactions, where IgE is the best known
mechanism to trigger their degranulation and release of a vast array of allergic mediators …