Retinal prostheses: Engineering and clinical perspectives for vision restoration

KY Wu, M Mina, JY Sahyoun, A Kalevar, SD Tran - Sensors, 2023 - mdpi.com
A retinal prosthesis, also known as a bionic eye, is a device that can be implanted to partially
restore vision in patients with retinal diseases that have resulted in the loss of …

Correlated activity in the degenerate retina inhibits focal response to electrical stimulation

J Ahn, S Cha, KE Choi, SW Kim, Y Yoo… - Frontiers in Cellular …, 2022 - frontiersin.org
Retinal prostheses have shown some clinical success in patients with retinitis pigmentosa
and age-related macular degeneration. However, even after the implantation of a retinal …

Focal electrical stimulation of human retinal ganglion cells for vision restoration

SS Madugula, AR Gogliettino, M Zaidi… - Journal of neural …, 2022 - iopscience.iop.org
Objective. Vision restoration with retinal implants is limited by indiscriminate simultaneous
activation of many cells and cell types, which is incompatible with reproducing the neural …

High spatial resolution artificial vision inferred from the spiking output of retinal ganglion cells stimulated by optogenetic and electrical means

AE Cojocaru, A Corna, M Reh, G Zeck - Frontiers in Cellular …, 2022 - frontiersin.org
With vision impairment affecting millions of people world-wide, various strategies aiming at
vision restoration are being undertaken. Thanks to decades of extensive research, electrical …

Precise control of neural activity using dynamically optimized electrical stimulation

NP Shah, AJ Phillips, S Madugula, A Lotlikar… - eLife, 2024 - elifesciences.org
Neural implants have the potential to restore lost sensory function by electrically evoking the
complex naturalistic activity patterns of neural populations. However, it can be difficult to …

High-fidelity reproduction of visual signals by electrical stimulation in the central primate retina

AR Gogliettino, SS Madugula, LE Grosberg… - Journal of …, 2023 - Soc Neuroscience
Electrical stimulation of retinal ganglion cells (RGCs) with electronic implants provides
rudimentary artificial vision to people blinded by retinal degeneration. However, current …

Spike sorting in the presence of stimulation artifacts: a dynamical control systems approach

M Shokri, AR Gogliettino, P Hottowy… - Journal of Neural …, 2024 - iopscience.iop.org
Objective. Bi-directional electronic neural interfaces, capable of both electrical recording and
stimulation, communicate with the nervous system to permit precise calibration of electrical …

[PDF][PDF] High-fidelity restoration of visual signals by electrical stimulation in the central primate retina

AR Gogliettino, SS Madugula, LE Grosberg, RS Vilkhu… - bioRxiv, 2022 - scholar.archive.org
Electrical stimulation of retinal ganglion cells (RGCs) with electronic implants provides
rudimentary artificial vision to people blinded by retinal degeneration, but cannot reproduce …

Learning to see via epiretinal implant stimulation in silico with model-based deep reinforcement learning

J Lavoie, M Besrour, W Lemaire, J Rouat… - Biomedical Physics …, 2024 - iopscience.iop.org
Objective: Diseases such as age-related macular degeneration and retinitis pigmentosa
cause the degradation of the photoreceptor layer. One approach to restore vision is to …

Retinal prostheses have shown some clinical success in patients with retinitis pigmentosa and age-related macular degeneration. However, even after the …

M Beyeler, J Weiland, SW Kim, Y Yoo… - … for sight restoration, 2023 - books.google.com
Retinal prostheses aim to restore vision in the blind with retinal degeneration, such as
retinitis pigmentosa (RP) and age-related macular degeneration (Weiland et al., 2011; …