Chronic migraine has a great detrimental influence on a patient's life, with a severe impact
on socioeconomic functioning and quality of life. Chronic migraine affects 1–2% of the …

Advancements in neurotechnologies for electrophysiology, neurochemical sensing,
neuromodulation, and optogenetics are revolutionizing scientific understanding of the brain …

Objective. Spinal cord and peripheral neurostimulation techniques have been practiced
since 1967 for the relief of pain, and some techniques are also used for improvement in …

Chronic migraine is a disabling neurologic condition that affects 2% of the general
population. Patients with chronic migraine have headaches on at least 15 days a month …

Background: Medically intractable chronic migraine (CM) is a disabling illness characterized
by headache≥ 15 days per month. Methods: A multicenter, randomized, blinded, controlled …

Background: Chronic migraine (CM) is a debilitating neurological disorder with few
treatment options. Peripheral nerve stimulation (PNS) of the occipital nerves is a potentially …

Introduction: The International Neuromodulation Society (INS) has determined that there is a
need for guidance regarding safety and risk reduction for implantable neurostimulation …

Background Recent studies evaluated short-term efficacy and safety of peripheral nerve
stimulation (PNS) of the occipital nerves for managing chronic migraine. We present 52 …

Background Drug-resistant chronic cluster headache (drCCH) is a devastating disorder for
which various destructive procedures have been tried unsuccessfully. Occipital nerve …

Many people who suffer from primary headache (ie, headache without an identifiable cause)
are resistant or intolerant to available drugs. During the past decade, central and peripheral …