Abstract The advent of Deep Learning (DL) is poised to dramatically change the delivery of
healthcare in the near future. Not only has DL profoundly affected the healthcare industry it …

Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

Chronic obstructive pulmonary disease (COPD) is the leading cause of respiratory mortality
worldwide. Genetic risk loci provide new insights into disease pathogenesis. We performed …

Chronic obstructive pulmonary disease (COPD) is a leading cause of mortality worldwide.
We performed a genetic association study in 15,256 cases and 47,936 controls, with …

The purpose of this statement is to describe and define the phenotypic abnormalities that
can be identified on visual and quantitative evaluation of computed tomographic (CT) …

Eosinophilic inflammation is thought to be a characteristic feature of asthma rather than
COPD. However, studies have shown that a subset of COPD patients with eosinophilic …

Importance Interstitial lung abnormalities have been associated with lower 6-minute walk
distance, diffusion capacity for carbon monoxide, and total lung capacity. However, to our …

We welcome the report by the SPIROMICS investigators in The Lancet Respiratory
Medicine, 1 repeating our 2010 ECLIPSE analysis2 describing exacerbations in chronic …

Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association …

Rationale: Deep learning is a powerful tool that may allow for improved outcome prediction.
Objectives: To determine if deep learning, specifically convolutional neural network (CNN) …