IL-33/ST2 axis in autoimmune disease

L Shakerian, H Kolahdooz, M Garousi, V Keyvani… - Cytokine, 2022 - Elsevier
Abstract Interleukin-33 (IL-33) is a member of the IL-1 family and plays an ambivalent role in
autoimmune diseases. IL-33 signals via the ST2 receptor and drives cytokine production in …

Alarmins in autoimmune diseases

MG Danieli, E Antonelli, MA Piga, I Claudi… - Autoimmunity …, 2022 - Elsevier
Alarmins are endogenous, constitutively expressed, chemotacting and immune activating
proteins or peptides released because of non-programmed cell death (ie infections, trauma …

Increased IL-33 expression in chronic obstructive pulmonary disease

J Xia, J Zhao, J Shang, M Li, Z Zeng… - … of Physiology-Lung …, 2015 - journals.physiology.org
Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease
characterized by inflammatory cell activation and the release of inflammatory mediators …

Emerging role of interleukin‐33 in autoimmune diseases

C Pei, M Barbour, KJ Fairlie‐Clarke, D Allan… - …, 2014 - Wiley Online Library
Summary Interleukin‐33 (IL‐33) is a member of the IL‐1 cytokine family. It predominantly
induces type 2 immune responses and thus is protective against atherosclerosis and …

Induced sputum levels of IL-33 and soluble ST2 in young asthmatic children

A Hamzaoui, A Berraies, W Kaabachi, M Haifa… - Journal of …, 2013 - Taylor & Francis
Objective: Interleukin-33 is an IL-1 family cytokine which signals via its T1/ST2 receptor, and
acts as a key regulator of inflammation, notably the type-2 response implicated in asthma …

Dichotomous function of IL-33 in health and disease: from biology to clinical implications

H Braun, IS Afonina, C Mueller, R Beyaert - Biochemical Pharmacology, 2018 - Elsevier
Abstract Interleukin (IL)-33 is a cytokine that is released from epithelial and endothelial cells
at barrier surfaces upon tissue stress or damage to operate as an alarmin. IL-33 has been …

The role of the IL-33/ST2 axis in autoimmune disorders: friend or foe?

X Liu, Y Xiao, Y Pan, H Li, SG Zheng, W Su - Cytokine & growth factor …, 2019 - Elsevier
Autoimmune diseases (ADs), which are common immune-mediated inflammatory
syndromes, are characterized by an imbalance between T effector (Th) 1/Th17 cells and T …

Role of interleukin 33 in respiratory allergy and asthma

H Makrinioti, M Toussaint, DJ Jackson… - The lancet Respiratory …, 2014 - thelancet.com
Since the discovery of interleukin 33 as the adopted ligand for the then orphan ST2 receptor,
many studies have implicated this cytokine in the pathogenesis of respiratory allergy and …

[PDF][PDF] Behçet's syndrome: a critical digest of the 2013-2014 literature

G Hatemi, E Seyahi, I Fresko, R Talarico… - Clin Exp …, 2014 - researchgate.net
This review focuses on the recent research on the epidemiology, outcome measures,
immunopathogenesis, genetics, clinical manifestations and management of Behçet's …

Serum IL-33 level and IL-33 gene polymorphisms in Behçet's disease

SS Koca, M Kara, F Deniz, M Ozgen, CF Demir… - Rheumatology …, 2015 - Springer
Behçet's disease (BD) is a chronic inflammatory disease. Increased productions of cytokines
including interleukin (IL)-1β and IL-18 are documented, and IL-1α and β gene …