Cancer therapy with accelerated charged particles is one of the most valuable biomedical
applications of nuclear physics. The technology has vastly evolved in the past 50 years, the …

Leptomeningeal metastasis (LM), or spread of cancer to the cerebrospinal fluid (CSF)–filled
space surrounding the central nervous system, is a fatal complication of cancer. Entry into …

This manuscript describes the Advanced Breast Cancer (ABC) international consensus
guidelines updated at the last two ABC international consensus conferences (ABC 6 in …

Simple Summary Hypothyroidism is a common toxicity experienced after radiotherapy for
head and neck malignancies. In this systemic review of the literature, we consolidated the …

Background Patients with HER2+ breast cancer (BC) frequently develop leptomeningeal
metastases (LM). While HER2-targeted therapies have demonstrated efficacy in the …

Leptomeningeal disease (LMD) is a devastating complication of cancer with a particularly
poor prognosis. Among solid tumours, malignant melanoma (MM) has one of the highest …

Opinion statement Melanoma has a high propensity to metastasize to the brain which
portends a poorer prognosis. With advanced radiation techniques and targeted therapies …

Clinical data supporting the best therapeutic approach in leptomeningeal disease (LMD;
also known as leptomeningeal metastases or leptomeningeal carcinomatosis) are lacking …

Simple Summary Leptomeningeal disease in melanoma (LMM) patients is characterized by
aggressiveness and dismal outcomes. Clinical studies and case reports demonstrate the …

Abstract Purpose of Review Headaches are a common, oftentimes debilitating symptom in
patients with leptomeningeal metastases. Recent Findings The third edition of the …