Process Development for the First GMP Synthesis of SGD-9501-TFA, Part 1: Synthesis of Two Oligopeptide Fragments

N Porter, W Guy, B Gill, K Bdeir, M Nguyen… - … Process Research & …, 2024 - ACS Publications
The discovery of novel auristatin-derived antibody drug conjugates (ADCs) with attenuated
bystander activity is an area of intense research. Recently, drug-linker SGD-9501 emerged …