Mechanisms in photodynamic therapy: part one—photosensitizers, photochemistry and cellular localization
AP Castano, TN Demidova, MR Hamblin - … and photodynamic therapy, 2004 - Elsevier
The use of non-toxic dyes or photosensitizers (PS) in combination with harmless visible light
that is known as photodynamic therapy (PDT) has been known for over a hundred years, but …
that is known as photodynamic therapy (PDT) has been known for over a hundred years, but …
[HTML][HTML] Direct and indirect effects of UV radiation on DNA and its components
In this survey, emphasis was placed on the main photoreactions of nucleic acid components,
involving both direct and indirect effects. The main UVB-and UVA-induced DNA …
involving both direct and indirect effects. The main UVB-and UVA-induced DNA …
Reactions of oxyl radicals with DNA
AP Breen, JA Murphy - Free radical biology and medicine, 1995 - Elsevier
The importance of radical-induced damage to DNA is apparent from the ever-increasing
number of publications in this area. This review focuses on the damage caused to DNA by …
number of publications in this area. This review focuses on the damage caused to DNA by …
Benzophenone photosensitized DNA damage
MC Cuquerella, V Lhiaubet-Vallet, J Cadet… - Accounts of chemical …, 2012 - ACS Publications
Although the carcinogenic potential of ultraviolet radiation is well-known, UV light may
interact with DNA by direct absorption or through photosensitization by endogenous or …
interact with DNA by direct absorption or through photosensitization by endogenous or …
Oxidative damage to DNA: formation, measurement, and biological significance
Deoxyribonucleic acid (DNA) appears to be a critical cellular target for the biological effects
(cellular lethality, mutagenesis, carcinogenesis, and ageing) of oxidation processes …
(cellular lethality, mutagenesis, carcinogenesis, and ageing) of oxidation processes …
X-ray activated nanoplatforms for deep tissue photodynamic therapy
JS Souris, L Leoni, HJ Zhang, A Pan, E Tanios… - Nanomaterials, 2023 - mdpi.com
Photodynamic therapy (PDT), the use of light to excite photosensitive molecules whose
electronic relaxation drives the production of highly cytotoxic reactive oxygen species (ROS) …
electronic relaxation drives the production of highly cytotoxic reactive oxygen species (ROS) …
Reaction of singlet oxygen with 2'-deoxyguanosine and DNA. Isolation and characterization of the main oxidation products
JL Ravanat, J Cadet - Chemical research in toxicology, 1995 - ACS Publications
The genotoxicity and the mutagenicity of 102, as the result of DNA oxidation, have been
determined (for recent reviews see refs 1—3). A major source of 1Ü2 is photo-sensitization …
determined (for recent reviews see refs 1—3). A major source of 1Ü2 is photo-sensitization …
Guanine oxidation: One‐and two‐electron reactions
G Pratviel, B Meunier - Chemistry–A European Journal, 2006 - Wiley Online Library
Guanine bases in DNA are the most sensitive to oxidation. A lot of effort has been devoted to
the understanding of the chemical modifications of guanine under different oxidizing …
the understanding of the chemical modifications of guanine under different oxidizing …
UV and ionizing radiations induced DNA damage, differences and similarities
JL Ravanat, T Douki - Radiation Physics and Chemistry, 2016 - Elsevier
Both UV and ionizing radiations damage DNA. Two main mechanisms, so-called direct and
indirect pathways, are involved in the degradation of DNA induced by ionizing radiations …
indirect pathways, are involved in the degradation of DNA induced by ionizing radiations …
Characterization of lysine− guanine cross-links upon one-electron oxidation of a guanine-containing oligonucleotide in the presence of a trilysine peptide
S Perrier, J Hau, D Gasparutto, J Cadet… - Journal of the …, 2006 - ACS Publications
Formation of DNA− protein cross-links involving the initial formation of a guanine radical
cation was investigated. For this purpose, riboflavin-mediated photosensitization of a TGT …
cation was investigated. For this purpose, riboflavin-mediated photosensitization of a TGT …