Anatomy and function of ventral tegmental area glutamate neurons
The ventral tegmental area (VTA) is well known for regulating reward consumption, learning,
memory, and addiction behaviors through mediating dopamine (DA) release in downstream …
memory, and addiction behaviors through mediating dopamine (DA) release in downstream …
Control of sleep and wakefulness
This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …
Wakefulness promoting systems cause low-voltage, fast activity in the …
Neurobiological mechanisms of nicotine reward and aversion
Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of
nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also …
nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also …
The neural and genetic basis of executive function: attention, cognitive flexibility, and response inhibition
Executive function is a collection of cognitive processes essential for higher order mental
function. Processes involved in executive function include, but are not limited to, working …
function. Processes involved in executive function include, but are not limited to, working …
Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety
C Nguyen, S Mondoloni, T Le Borgne, I Centeno… - Neuron, 2021 - cell.com
Nicotine stimulates dopamine (DA) neurons of the ventral tegmental area (VTA) to establish
and maintain reinforcement. Nicotine also induces anxiety through an as yet unknown …
and maintain reinforcement. Nicotine also induces anxiety through an as yet unknown …
An inhibitory brainstem input to dopamine neurons encodes nicotine aversion
Nicotine stimulates the dopamine (DA) system, which is essential for its rewarding effect.
Nicotine is also aversive at high doses; yet, our knowledge about nicotine's dose-dependent …
Nicotine is also aversive at high doses; yet, our knowledge about nicotine's dose-dependent …
Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
JA Dani, D Bertrand - Annu. Rev. Pharmacol. Toxicol., 2007 - annualreviews.org
Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from
numerous subunit combinations that compose channel-receptor complexes with varied …
numerous subunit combinations that compose channel-receptor complexes with varied …
The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse?
RC Pierce, V Kumaresan - Neuroscience & biobehavioral reviews, 2006 - Elsevier
In this review we will critically assess the hypothesis that the reinforcing effect of virtually all
drugs of abuse is primarily dependent on activation of the mesolimbic dopamine system …
drugs of abuse is primarily dependent on activation of the mesolimbic dopamine system …
Neuronal nicotinic receptors: from structure to pathology
C Gotti, F Clementi - Progress in neurobiology, 2004 - Elsevier
Neuronal nicotinic receptors (NAChRs) form a heterogeneous family of ion channels that are
differently expressed in many regions of the central nervous system (CNS) and peripheral …
differently expressed in many regions of the central nervous system (CNS) and peripheral …
Brain nicotinic acetylcholine receptors: native subtypes and their relevance
Neuronal nicotinic acetylcholine receptors comprise a heterogeneous class of cationic
channels that is present throughout the nervous system. These channels are involved both …
channels that is present throughout the nervous system. These channels are involved both …