Calcium (Ca++) is one of the major signal molecules that regulate various aspects of cell
functions including cell cycle progression, arrest, and apoptosis in wide variety of cells. This …

After ovulation, mammalian oocytes will undergo a time-dependent process of aging if they
are not fertilized. This postovulatory aging (POA) seriously affects the oocyte quality and …

If fertilization does not occur for a prolonged period in vivo or in vitro, the postovulatory
oocytes will deteriorate, which called the postovulatory aging. This process disrupts the …

Nisin is a food preservative produced by Lactococcus lactis subsp. lactis. Previous blood
biochemical research revealed that nisin has physiological effects in mammals; although the …

Mechanisms for post-maturation oocyte aging (PMOA) are not fully understood, and whether
autophagy plays any role in PMOA is unknown. To explore the role of autophagy in PMOA …

Increased oxidative stress (OS) due to in vitro culture conditions can affect the quality of
denuded eggs during various assisted reproductive technologies (ARTs). Presence of intact …

The present study was aimed to find out whether increased level of reactive oxygen species
(ROS) particularity hydrogen peroxide (H 2 O 2) could persuade postovulatory aging …

In spite of great efforts, the mechanisms for postovulatory oocyte aging are not fully
understood. Although our previous work showed that the FasL/Fas signaling facilitated …

Studies suggested that postovulatory oocyte aging might be prevented by maintaining a
high maturation-promoting factor (MPF) activity. Whether AMP-activated protein kinase …

Maintenance of metaphase-II (M-II) arrest in ovum is required to present itself as a right
gamete for successful fertilization in mammals. Surprisingly, instability of meiotic cell cycle …