Sex/gender differences in the time-course for the development of substance use disorder: a focus on the telescoping effect
EB Towers, IL Williams, EI Qillawala, EF Rissman… - Pharmacological …, 2023 - ASPET
Sex/gender effects have been demonstrated for multiple aspects of addiction, with one of the
most commonly cited examples being the “telescoping effect” where women meet criteria …
most commonly cited examples being the “telescoping effect” where women meet criteria …
Pharmacological treatments for methamphetamine addiction: current status and future directions
J Ballester, G Valentine, M Sofuoglu - Expert review of clinical …, 2017 - Taylor & Francis
Introduction: Methamphetamine (MA) abuse remains a global health challenge despite
intense research interest in the development of pharmacological treatments. This review …
intense research interest in the development of pharmacological treatments. This review …
[HTML][HTML] Interactions of neuroimmune signaling and glutamate plasticity in addiction
Chronic use of drugs of abuse affects neuroimmune signaling; however, there are still many
open questions regarding the interactions between neuroimmune mechanisms and …
open questions regarding the interactions between neuroimmune mechanisms and …
Cannabidiol treatment reduces the motivation to self-administer methamphetamine and methamphetamine-primed relapse in rats
GL Hay, SJ Baracz, NA Everett… - Journal of …, 2018 - journals.sagepub.com
Background: Methamphetamine is an addictive stimulant that can cause many adverse
physical, psychological and psychosocial effects. Preliminary evidence shows cannabidiol …
physical, psychological and psychosocial effects. Preliminary evidence shows cannabidiol …
Neural mechanisms underlying incubation of methamphetamine craving: a mini-review
RD Altshuler, H Lin, X Li - Pharmacology Biochemistry and Behavior, 2020 - Elsevier
Cue-induced drug craving and seeking progressively increases during abstinence. This
“incubation of drug craving” phenomenon has been observed in both laboratory animals …
“incubation of drug craving” phenomenon has been observed in both laboratory animals …
Methamphetamine self-administration elicits sex-related changes in postsynaptic glutamate transmission in the prefrontal cortex
JI Pena-Bravo, R Penrod, CM Reichel, A Lavin - eneuro, 2019 - eneuro.org
Preclinical and clinical research has shown that females are more vulnerable to the
rewarding effects of stimulants, and it has been proposed that estrogens may play a role in …
rewarding effects of stimulants, and it has been proposed that estrogens may play a role in …
Extended access self-administration of methamphetamine is associated with age-and sex-dependent differences in drug taking behavior and recognition memory in …
SR Westbrook, MR Dwyer, LR Cortes… - Behavioural brain …, 2020 - Elsevier
Individuals who begin drug use during early adolescence experience more adverse
consequences compared to those initiating later, especially if they are female. The …
consequences compared to those initiating later, especially if they are female. The …
AMPA receptor and metabotropic glutamate receptor 1 adaptations in the nucleus accumbens core during incubation of methamphetamine craving
Cue-induced drug craving progressively intensifies after withdrawal from self-administration
of cocaine, methamphetamine, and other drugs of abuse, a phenomenon termed incubation …
of cocaine, methamphetamine, and other drugs of abuse, a phenomenon termed incubation …
Persistent neuroadaptations in the nucleus accumbens core accompany incubation of methamphetamine craving in male and female rats
JR Funke, EK Hwang, AM Wunsch, R Baker… - eneuro, 2023 - eneuro.org
Relapse is a major problem in treating methamphetamine use disorder.“Incubation of
craving” during abstinence is a rat model for persistence of vulnerability to craving and …
craving” during abstinence is a rat model for persistence of vulnerability to craving and …
[HTML][HTML] Oxytocin and addiction: potential glutamatergic mechanisms
Recently, oxytocin (OXT) has been investigated for its potential therapeutic role in addiction.
OXT has been found to diminish various drug-seeking and drug-induced behaviors …
OXT has been found to diminish various drug-seeking and drug-induced behaviors …