The clustered regularly interspaced short palindromic repeats system has demonstrated
considerable advantages over other nuclease-based genome editing tools due to its high …

Hepatocellular carcinoma (HCC) is now a common cause of cancer death, with no obvious
change in patient survival over the past few years. Although the traditional therapeutic …

Bone is a dynamic tissue, whose homeostasis is maintained by a fine balance between
osteoclast (OC) and osteoblast (OB) activity. The endocannabinoid/endovanilloid (EC/EV) …

Diabetic ulcers bring about high morbidity and mortality in patients and cause a great
economic burden to society as a whole. Since existing treatments cannot fulfil patient …

Osteosarcoma (OS) is the most common malignant bone tumor in children and young adults.
Despite that high-risk factors have been identified, no test for early detection is available …

Background Osteosarcoma is generally reported among younger individuals and has a very
poor prognosis, particularly for the development of metastasis. However, more effective …

Simple Summary Osteosarcoma (OS), which accounts for about 35% of bone malignancy,
shows aggressive progression in adults, adolescents, and children. Neoadjuvant …

Accumulating evidence has indicated that circular RNAs (circRNAs) serve crucial roles in
the progression of a diverse range of different types of cancer, including osteosarcoma (OS) …

Osteosarcoma (OS) is the most common primary malignant bone tumor in children and
teenagers and is characterized by high malignant potential, rapid disease progression and …

The use of liquid biopsy in cancer research has grown exponentially, offering potential for
early detection, treatment stratification, and monitoring residual disease and recurrence …