Vascular biology of the placenta

H Weiler - Endothelial Cells in Health and Disease, 2005 - taylorfrancis.com
The placenta is a gender-specific transitory organ with the sole purpose of enabling the
growth and development of the fetus. It mediates the efficient transfer and exchange of …

Regulation of human trophoblast migration and invasiveness

C Chakraborty, LM Gleeson… - Canadian journal of …, 2002 - cdnsciencepub.com
Le placenta humain est une structure invasive dans laquelle les cellules du trophoblaste
extravilleux (TEV), très prolifératives, migratrices et invasives, migrent et envahissent l'utérus …

Placental metabolism and its regulation in health and diabetes

G Desoye, E Shafrir - Molecular aspects of medicine, 1994 - Elsevier
During embryogenesis in all mammalian species the placenta is formed inside the uterus by
apposition or fusion of maternally and embryonically-derived tissues. Genetically, normal …

The emerging role of endothelin-1 in the pathogenesis of pre-eclampsia

L Saleh, K Verdonk, W Visser… - Therapeutic …, 2016 - journals.sagepub.com
Pre-eclampsia (PE) is the most frequently encountered medical complication during
pregnancy. It is characterized by a rise in systemic vascular resistance with a relatively low …

Gap junctional communication during human trophoblast differentiation: influence of human chorionic gonadotropin

L Cronier, B Bastide, JC Herve, J Deleze… - …, 1994 - academic.oup.com
During pregnancy, the trophoblast develops from the fusion of cytotrophoblastic cells into a
syncytiotrophoblast. As the exchange of molecules through gap junctions is considered to …

Expression and relationship between endothelin-1 messenger ribonucleic acid (mRNA) and inducible/endothelial nitric oxide synthase mRNA isoforms from normal …

M Napolitano, F Miceli, A Calce, A Vacca… - The Journal of …, 2000 - academic.oup.com
Preeclampsia is a mainly vascular disease of pregnancy, probably caused by an imbalance
between vasodilator and vasoconstrictor agents that results in generalized vasospasm and …

Endothelin-1 and ETA Receptor Expression in Vascular Smooth Muscle Cells from Human Placenta: A New ETA Receptor Messenger Ribonucleic Acid Is …

C Bourgeois, B Robert, R Rebourcet… - The Journal of …, 1997 - academic.oup.com
Abstract Endothelin-1 (ET-1) is a potent vasoactive peptide in stem villi vessels, which are
considered to be the major sites of placental vascular resistance. To investigate the …

Adriana and Luisa Castellucci award lecture 1999: role of oxygen in the regulation of trophoblast gene expression and invasion

CH Graham, LM Postovit, H Park, MT Canning… - Placenta, 2000 - Elsevier
Changes in oxygen levels characterize normal and pathological human placentation. For
example, relatively low Po 2values are present around the blastocyst during implantation …

Pregnancy outcomes and community health: the POUCH study of preterm birth

C Holzman, B Bullen, R Fisher… - Paediatric and …, 2001 - Wiley Online Library
In light of the social/ethnic disparity in preterm delivery (PTD) rates, the Pregnancy
Outcomes and Community Health (POUCH) Study takes a broad view of the determinants of …

Endothelin-1: a key pathological factor in pre-eclampsia?

A Jain - Reproductive biomedicine online, 2012 - Elsevier
Endothelin (ET)-1 has been implicated in a diverse range of signalling events in a wide
variety of target tissues. Given its potent vasoactive function and the prevalence of …