Same substrate, many reactions: oxygen activation in flavoenzymes
Over time, organisms have evolved strategies to cope with the abundance of dioxygen on
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
Earth. Oxygen-utilizing enzymes tightly control the reactions involving O2 mostly by …
Flavin dependent monooxygenases
MME Huijbers, S Montersino, AH Westphal… - Archives of biochemistry …, 2014 - Elsevier
Flavin-dependent monooxygenases catalyze a wide variety of chemo-, regio-and
enantioselective oxygenation reactions. As such, they are involved in key biological …
enantioselective oxygenation reactions. As such, they are involved in key biological …
[HTML][HTML] Flavoprotein monooxygenases: versatile biocatalysts
Flavoprotein monooxygenases (FPMOs) are single-or two-component enzymes that
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …
catalyze a diverse set of chemo-, regio-and enantioselective oxyfunctionalization reactions …
Toward scalable biocatalytic conversion of 5-hydroxymethylfurfural by galactose oxidase using coordinated reaction and enzyme engineering
WR Birmingham, A Toftgaard Pedersen… - Nature …, 2021 - nature.com
Hydroxymethylfurfural (HMF) has emerged as a crucial bio-based chemical building block in
the drive towards developing materials from renewable resources, due to its direct …
the drive towards developing materials from renewable resources, due to its direct …
Chemistry and enzymology of disulfide cross-linking in proteins
Cysteine thiols are among the most reactive functional groups in proteins, and their pairing
in disulfide linkages is a common post-translational modification in proteins entering the …
in disulfide linkages is a common post-translational modification in proteins entering the …
The enigmatic reaction of flavins with oxygen
The reaction of flavoenzymes with oxygen remains a fascinating area of research because
of its relevance for reactive oxygen species (ROS) generation. Several exciting recent …
of its relevance for reactive oxygen species (ROS) generation. Several exciting recent …
Heteroatom–heteroatom bond formation in natural product biosynthesis
Natural products that contain functional groups with heteroatom-heteroatom linkages (X–X,
where X= N, O, S, and P) are a small yet intriguing group of metabolites. The reactivity and …
where X= N, O, S, and P) are a small yet intriguing group of metabolites. The reactivity and …
Molecular recognition and ligand association
R Baron, JA McCammon - Annual review of physical chemistry, 2013 - annualreviews.org
We review recent developments in our understanding of molecular recognition and ligand
association, focusing on two major viewpoints:(a) studies that highlight new physical insight …
association, focusing on two major viewpoints:(a) studies that highlight new physical insight …
Engineering glucose oxidase for bioelectrochemical applications
N Mano - Bioelectrochemistry, 2019 - Elsevier
There is still a growing interest in developing glucose sensors using glucose oxidase. Since
2012, over 1000 papers are published every year, while efficient commercial sensors exist …
2012, over 1000 papers are published every year, while efficient commercial sensors exist …
The oxygen dilemma: a severe challenge for the application of monooxygenases?
D Holtmann, F Hollmann - ChemBioChem, 2016 - Wiley Online Library
Monooxygenases are promising catalysts because they in principle enable the organic
chemist to perform highly selective oxyfunctionalisation reactions that are otherwise difficult …
chemist to perform highly selective oxyfunctionalisation reactions that are otherwise difficult …