Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …

Epilepsy is the third most common chronic brain disorder, and is characterized by an
enduring predisposition to generate seizures. Despite progress in pharmacological and …

Rasmussen's encephalitis is a rare chronic neurological disorder, characterised by
unilateral inflammation of the cerebral cortex, drug-resistant epilepsy, and progressive …

During the last decade, experimental research has demonstrated a prominent role of glial
cells, activated in brain by various injuries, in the mechanisms of seizure precipitation and …

The rapid expansion in the number of encephalitis disorders associated with autoantibodies
against neuronal proteins has led to an incremental increase in use of the term “autoimmune …

This review reports the available evidence on the activation of the innate and adaptive
branches of the immune system and the related inflammatory processes in epileptic …

Rasmussen encephalitis (RE) is a rare but severe immune-mediated brain disorder leading
to unilateral hemispheric atrophy, associated progressive neurological dysfunction and …

Objective To determine the frequency and clinical relevance of immunoglobulin (Ig) G, IgA,
and IgM N-methyl-d-aspartate receptor (NMDAR) antibodies in several diseases, and …

Previous studies from our group, focusing on neuro-glial remodelling in human temporal
lobe epilepsy (TLE), have shown the presence of immature vascular cells in various areas of …