[HTML][HTML] Review of COVID-19 testing and diagnostic methods

O Filchakova, D Dossym, A Ilyas, T Kuanysheva… - Talanta, 2022 - Elsevier
More than six billion tests for COVID-19 has been already performed in the world. The
testing for SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) virus and …

Viral infection neutralization tests: A focus on severe acute respiratory syndrome‐coronavirus‐2 with implications for convalescent plasma therapy

D Focosi, F Maggi, P Mazzetti… - Reviews in medical …, 2021 - Wiley Online Library
Viral neutralization tests (VNTs) have long been considered old‐fashioned tricks in the
armamentarium of fundamental virology, with laboratory implementation for a limited array of …

[PDF][PDF] Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters

MS Piepenbrink, JG Park, FS Oladunni… - Cell Reports …, 2021 - cell.com
SARS-CoV-2 infection results in viral burden in the respiratory tract, enabling transmission
and leading to substantial lung pathology. The 1212C2 fully human monoclonal antibody …

Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes

K Chiem, D Morales Vasquez, JG Park, RN Platt… - Journal of …, 2021 - Am Soc Microbiol
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
pathogen responsible for coronavirus disease 2019 (COVID-19), has devastated public …

[HTML][HTML] Development of an IgG-Fc fusion COVID-19 subunit vaccine, AKS-452

DG Alleva, AR Delpero, MM Scully, S Murikipudi… - Vaccine, 2021 - Elsevier
AKS-452 is a biologically-engineered vaccine comprising an Fc fusion protein of the SARS-
CoV-2 viral spike protein receptor binding domain antigen (Ag) and human IgG1 Fc …

Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal …

MS Piepenbrink, JG Park, A Deshpande, A Loos… - PLoS …, 2022 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) marks the third novel β-
coronavirus to cause significant human mortality in the last two decades. Although vaccines …

[PDF][PDF] Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2

JG Park, FS Oladunni, MA Rohaim… - IScience, 2021 - cell.com
Global deployment of an effective and safe vaccine is necessary to curtail the coronavirus
disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] A randomized phase I/II safety and immunogenicity study of the Montanide-adjuvanted SARS-CoV-2 spike protein-RBD-Fc vaccine, AKS-452

EA Feitsma, YF Janssen, HH Boersma, Y van Sleen… - Vaccine, 2023 - Elsevier
Background Previous interim data from a phase I study of AKS-452, a subunit vaccine
comprising an Fc fusion of the respiratory syndrome coronavirus 2 (SARS-CoV-2) spike …

Rapid Generation of Circulating and Mucosal Decoy Human ACE2 using mRNA Nanotherapeutics for the Potential Treatment of SARS‐CoV‐2

J Kim, A Jozic, A Mukherjee, D Nelson… - Advanced …, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can cause lethal
pulmonary damage in humans. It contains spike proteins on its envelope that bind to human …

Modeling SARS-CoV-2 and influenza infections and antiviral treatments in human lung epithelial tissue equivalents

H Zarkoob, A Allué-Guardia, YC Chen… - Communications …, 2022 - nature.com
There is a critical need for physiologically relevant, robust, and ready-to-use in vitro cellular
assay platforms to rapidly model the infectivity of emerging viruses and develop new …